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SHEET /m/caffeine · PubChem CID 2519 · CAS 58-08-2 · REV 2026.07

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Caffeine from source

C8H10N4O2 · 194.19 g/mol

Guaranine · 1,3,7-Trimethylxanthine · Methyltheobromine · Theine

chemical compound used as a stimulant

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Fig. 1 · 2D structure RDKit

CN1C=NC2=C1C(=O)N(C(=O)N2C)C

Where you'll find it

Curated by MoleculeFinder from source

Still in your system computed

Caffeine clears on a half-life of 5 h. Every 5 hours, half of what's left is gone. Put in what you had:

95 mg left
100% of your 95 mg remains

The dose makes the poison inferred

A reported rat oral LD50 for Caffeine is 192 mg/kg, the dose lethal to half the animals tested. Scaled by body mass alone:

13.4 g141 cups
a median lethal dose scaled to 154 lb (13,440 mg)

“The dose makes the poison” is a cross-species estimate shown as neutral science, not a threshold anyone should act on. Real toxicity depends on the person, not body mass alone.

Signature properties

Half-life5 hfrom source

Toxicity & hazards

Toxicity · LD50

192 mg/kg · moderately toxic · LD50 rat oral from source

The dose lens above scales this to a body weight.

4 more reported values
  • 127 mg/kgLD50 · oral · mouse
  • 105 mg/kgLD50 · iv · rat
  • 260 mg/kgLD50 · other · rat
  • 300 mg/kgLD50 · other · rat
DangerToxicIrritantHealth hazardH301, H302, H332, H360from source

Keep roaming

Where Caffeine leads

Caffeine is the world's most widely used psychoactive drug, and the only one routinely served to children (as chocolate) and at the breakfast table.