SHEET /m/caffeine · PubChem CID 2519 · CAS 58-08-2 · REV 2026.07
Caffeine
from sourceC8H10N4O2 · 194.19 g/mol
guaranine · methyltheobromine · theine · teína
What is Caffeine?
The molecule behind coffee's lift: it keeps you feeling alert by getting in the way of your brain's own sleepiness signal. Found in coffee, tea, chocolate, cocoa, and soft drinks. from source
Fig. 1 · 2D structure RDKit
CN1C=NC2=C1C(=O)N(C(=O)N2C)CWhere you'll find it
Curated by MoleculeFinder from source
Still in the system computed
For a typical adult, Caffeine clears on a half-life of about 5 h: every 5 hours, half of what is left is gone. Try an amount:
An illustration of half-life, not a prediction of anyone's level.
The dose makes the poison inferred
A reported rat oral LD50 for Caffeine is 192 mg/kg, the dose lethal to half the animals tested. Scaled by body mass alone:
“The dose makes the poison” is a cross-species estimate shown as neutral science, not a threshold anyone should act on. Real toxicity depends on the person, not body mass alone.
Signature properties
Toxicity & hazards
Toxicity · LD50
192 mg/kg · moderately toxic · LD50 rat oral from source
The dose lens above scales this to a body weight.
4 more reported values
- 127 mg/kgLD50 · oral · mouse
- 105 mg/kgLD50 · iv · rat
- 260 mg/kgLD50 · other · rat
- 300 mg/kgLD50 · other · rat
Keep roaming
Where Caffeine leads
Compare with
Caffeine is the world's most widely used psychoactive drug, and the only one routinely served to children (as chocolate) and at the breakfast table.