SHEET /m/theophylline · PubChem CID 2153 · CAS 58-55-9 · REV 2026.07
Theophylline from source
C7H8N4O2 · 180.16 g/mol
1,3-Dimethylxanthine · Elixophyllin · Theophyllin · Theolair
chemical compound
Fig. 1 · 2D structure RDKit
CN1C2=C(C(=O)N(C1=O)C)NC=N2
Where you'll find it
Curated by MoleculeFinder from source
Still in your system computed
Theophylline clears on a half-life of 8 h. Every 8 hours, half of what's left is gone. Put in what you had:
The dose makes the poison inferred
A reported mouse oral LD50 for Theophylline is 332 mg/kg, the dose lethal to half the animals tested. Scaled by body mass alone:
“The dose makes the poison” is a cross-species estimate shown as neutral science, not a threshold anyone should act on. Real toxicity depends on the person, not body mass alone.
Signature properties
Toxicity & hazards
Toxicity · LD50
332 mg/kg · low toxicity · LD50 mouse oral from source
The dose lens above scales this to a body weight.
3 more reported values
- 136 mg/kgLD50 · iv · mouse
- 180 mg/kgLD50 · other · mouse
- 271 mg/kgLD50 · other · mouse
Keep roaming
Where Theophylline leads
Theophylline is the third of the three dietary methylxanthines, found in trace amounts in tea and used as a drug to open the airways. It shares caffeine's chemistry but lingers longer in the body.