SHEET /m/theophylline · PubChem CID 2153 · CAS 58-55-9 · REV 2026.07
Theophylline
from sourceC7H8N4O2 · 180.16 g/mol
Elixophyllin · Elixophylline · Lanophyllin · Nuelin
What is Theophylline?
A close relative of caffeine that turns up in tea, and a mild stimulant of its own. Theophylline (C7H8N4O2, 180 g/mol) is a plant alkaloid made by plants. Found in tea, coffee, and cocoa. from source
Fig. 1 · 2D structure RDKit
CN1C2=C(C(=O)N(C1=O)C)NC=N2Where you'll find it
Curated by MoleculeFinder from source
Still in the system computed
For a typical adult, Theophylline clears on a half-life of about 8 h: every 8 hours, half of what is left is gone. Try an amount:
An illustration of half-life, not a prediction of anyone's level.
Relative acute toxicity from source
Animal study data · LD50
- Reported LD50
- 332 mg/kg · low toxicity
- Species
- mouse
- Route
- oral
An LD50 describes acute toxicity under experimental conditions and is not a safe or dangerous dose for a person.
Signature properties
Toxicity & hazards
Toxicity · LD50
332 mg/kg · low toxicity · LD50 mouse oral from source
3 more reported values
- 136 mg/kgLD50 · iv · mouse
- 180 mg/kgLD50 · other · mouse
- 271 mg/kgLD50 · other · mouse
Keep roaming
Where Theophylline leads
Compare with
Theophylline is the third of the three dietary methylxanthines, found in trace amounts in tea and used as a drug to open the airways. It shares caffeine's chemistry but lingers longer in the body.