SHEET /m/theobromine · PubChem CID 5429 · CAS 83-67-0 · REV 2026.07
Theobromine
from sourceC7H8N4O2 · 180.16 g/mol
diurobromine · Santheose · Theosalvose · Theostene
What is Theobromine?
Chocolate's gentle stimulant, a milder cousin of caffeine that gives cocoa its lingering lift and faint bitterness. Found in chocolate, cocoa, coffee, and tea. from source
Fig. 1 · 2D structure RDKit
CN1C=NC2=C1C(=O)NC(=O)N2CWhere you'll find it
Curated by MoleculeFinder from source
Still in the system computed
For a typical adult, Theobromine clears on a half-life of about 7.2 h: every 7.2 hours, half of what is left is gone. Try an amount:
An illustration of half-life, not a prediction of anyone's level.
The dose makes the poison inferred
A reported dog oral LD50 for Theobromine is 300 mg/kg, the dose lethal to half the animals tested. Scaled by body mass alone:
“The dose makes the poison” is a cross-species estimate shown as neutral science, not a threshold anyone should act on. Real toxicity depends on the person, not body mass alone.
Signature properties
Toxicity & hazards
Toxicity · LD50
300 mg/kg · moderately toxic · LD50 dog oral from source
The dose lens above scales this to a body weight.
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Where Theobromine leads
Compare with
Theobromine is caffeine's gentler cousin and the molecule that gives chocolate its lift. Named for the cacao tree (Theobroma, food of the gods), it clears the body more slowly than caffeine, and the dose in dark chocolate is enough to poison a dog.