SHEET /m/propylene-glycol · PubChem CID 1030 · CAS 57-55-6 · REV 2026.07
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Propylene glycol from source
C3H8O2 · 76.09 g/mol
1,2-propanediol · propane-1,2-diol · 1,2-Propylene glycol · 1,2-dihydroxypropane
pair of enantiomers
CategoryFood & flavor
Chemical familyAlcohols
Fig. 1 · 2D structure RDKit
CC(CO)O
Where you'll find it
Not yet mapped to everyday foods or products.
The dose makes the poison inferred
A reported rat oral LD50 for Propylene glycol is 22,000 mg/kg, the dose lethal to half the animals tested. Scaled by body mass alone:
1540.0 g
a median lethal dose scaled to 154 lb (1,540,000 mg)
“The dose makes the poison” is a cross-species estimate shown as neutral science, not a threshold anyone should act on. Real toxicity depends on the person, not body mass alone.
Toxicity & hazards
Toxicity · LD50
22,000 mg/kg · very low toxicity · LD50 rat oral from source
The dose lens above scales this to a body weight.
2 more reported values
- 6,423 mg/kgLD50 · iv · rat
- 6,660 mg/kgLD50 · other · rat
DangerIrritantHealth hazardH336, H370, H372from source
Keep roaming