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SHEET /m/propylene-glycol · PubChem CID 1030 · CAS 57-55-6 · REV 2026.07

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Propylene glycol

from source

C3H8O2 · 76.09 g/mol

methyl ethyl glycol · MEG · methylethylene glycol · PG

What is Propylene glycol?

The carrier liquid in vape juice, fog machines, and many liquid medicines. It holds water, so it keeps things moist without being sweet. Found in processed snacks. from source

Chemical familyAlcohols
LeaderboardsBiggestDeadliest

Fig. 1 · 2D structure RDKit

SMILESCC(CO)O

Where you'll find it

Curated by MoleculeFinder from source

The dose makes the poison inferred

A reported rat oral LD50 for Propylene glycol is 22,000 mg/kg, the dose lethal to half the animals tested. Scaled by body mass alone:

1540.0 g
a median lethal dose scaled to 154 lb (1,540,000 mg)

“The dose makes the poison” is a cross-species estimate shown as neutral science, not a threshold anyone should act on. Real toxicity depends on the person, not body mass alone.

Toxicity & hazards

Toxicity · LD50

22,000 mg/kg · very low toxicity · LD50 rat oral from source

The dose lens above scales this to a body weight.

2 more reported values
  • 6,423 mg/kgLD50 · iv · rat
  • 6,660 mg/kgLD50 · other · rat
DangerIrritantHealth hazardH336, H370, H372from source

Keep roaming

Where Propylene glycol leads

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Sources & methodology

PubChem CID
1030
Wikidata
Q161495
Structure
PubChem → RDKit
LD50
PubChem
Similar molecules
MoleculeFinder fingerprint similarity
Everyday relationships
MoleculeFinder editorial curation
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