moleculefinder

Oxycodone

C18H21NO4315.4 g/mol Calculated

Also called Oxycontin, dihydroxycodeinone and dihydrohydroxycodeinone.

An opioid painkiller sold as OxyContin and Percocet, made by modifying thebaine from the opium poppy. Its extended-release form is at the centre of the American opioid epidemic.

Sources and notes
  • The introductionfrom sourceMoleculeFinder curated
  • Other namesfrom sourceWikidataIts English label and aliases on Wikidata.
  • Formula and weightcomputedPubChem
  • 2D drawingcomputedPubChem structure, drawn by RDKit
  • 3D modelfrom sourcePubChem 3D conformerLoaded after the page has painted, and on a phone only when you ask for it; the 2D drawing shows until it arrives.

Where you encounter it

Dispensed on prescription, not sold on a shelf. Oxycodone on the product labels we hold.

Medicines

PercocetAdded by the makerActive ingredient
RoxicodoneAdded by the makerActive ingredient

Every product and list we hold

Sources and notes
  • The product labels and their strengthsfrom sourceDailyMed (FDA label)Each label lists the molecule as an ingredient, and an active ingredient at the strength shown.
  • How it gets therefrom sourceMoleculeFinder curatedEach mark is set by hand on our lists, never inferred; a label's ingredient is added by the maker. A row with no mark data says Not marked.
  • The line abovefrom sourceMoleculeFinder curatedFrom the group the molecule belongs to.

Explore its structure

Choose a part to light it up.

A C=O with a carbon on each side. Its oxygen accepts hydrogen bonds but has no hydrogen to give, and it resists oxidation better than an aldehyde.

From: standard chemistry.

Sources and notes
  • The drawingcomputedPubChem structure, drawn by RDKitThe page's one shipped drawing, with the chosen part lit in amber under it.
  • The partscomputedFound by ruleEach part is found by a chemical pattern, never picked by hand atom by atom; its words say where they come from.

Compare a related molecule

Oxycodone

Hydrocodone

One hydroxyl group apart.

Oxycodone and hydrocodone are nearly the same molecule, both semi-synthetic opioids made from thebaine, differing by one hydroxyl group that oxycodone carries.

Oxycodone vs Hydrocodone, side by side

Also compared

Sources and notes
  • The sentencefrom sourceMoleculeFinder comparison notesThe pair's answer line.
  • The two drawingscomputedPubChem structures, drawn by RDKitDrawn the same way round; the amber marks where the two differ.
  • The captionfrom sourceMoleculeFinder curated

Properties and sources

Calculated by PubChem

Molecular formula
C18H21NO4
Molecular weight
315.4 g/mol
XLogP3octanol/water, log units
1.2
Polar surface areatopological
59 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
1
Complexity
553

Measured LD50, HSDB via PubChem

320 mg/kg pure oxycodone, mouse, another route

An LD50 is an animal study measurement, not a dose for a person.

Reported Hazard label (GHS), ECHA, HSDB via PubChem

Warning Irritant pictogram (GHS07) and Health hazard pictogram (GHS08); hazard statements H302, H336, H362

Reported Licence

The US Food and Drug Administration licenses Oxycodone for human use (NDA 021011, authorized August 31, 2000), as Roxicodone. Drugs@FDA

Groups it belongs to

Category
Prescription medicine
Family
Opioids
Chemical groups
Alcohols, Aromatics, Ketones, Ethers
Elements
Nitrogen
Hazard classes
Irritant, Health hazard, GHS Warning
SMILESCN1CC[C@]23[C@@H]4C(=O)CC[C@]2([C@H]1CC5=C3C(=C(C=C5)OC)O4)O

PubChem CID 5284603 · Wikidata Q407535 · InChIKey BRUQQQPBMZOVGD-XFKAJCMBSA-N · Data refreshed

How MoleculeFinder sources and labels its data

Questions
What is Oxycodone?
An opioid painkiller sold as OxyContin and Percocet, made by modifying thebaine from the opium poppy. Its extended-release form is at the centre of the American opioid epidemic.
How toxic is Oxycodone?
The reported LD50 of Oxycodone is 320 mg/kg (mouse, other). An LD50 is an animal study measurement, not a dose for a person. Its GHS hazard label carries the signal word Warning and the hazard pictograms Irritant and Health hazard. from sourcefrom source
What kind of molecule is Oxycodone?
Oxycodone has the formula C18H21NO4 and a molecular weight of 315.4 g/mol. MoleculeFinder files it under opioids, in the prescription medicine group. from sourcefrom sourcefrom sourcefrom source
What else is Oxycodone called?
Oxycodone is also called dihydroxycodeinone, dihydrohydroxycodeinone and Oxycontin. from source
Who licenses Oxycodone as a medicine?
The US Food and Drug Administration licenses Oxycodone for human use (NDA 021011, authorized August 31, 2000), as Roxicodone. from source
Sources and notes
  • Calculated valuescomputedPubChemComputed from the structure, so no laboratory conditions apply; complexity is PubChem's own structural score.
  • LD50from sourceHSDB via PubChemOther values the sources report: mouse, another route, 426 mg/kg. The page shows the one LD50 the site uses everywhere.
  • Hazard labelfrom sourceECHA, HSDB via PubChemThe label combines these classifications.
  • ECHAfrom sourceAttributionSource: European Chemicals Agency, echa.europa.eu.
  • Licencefrom sourceDrugs@FDARead 2026-10-21.
  • Data refreshedfrom sourceMoleculeFinder2026-11-09

Keep exploring

One hydroxyl group apart.HydrocodoneC18H21NO3Compared side by side with oxycodoneTramadolC16H25NO2Also an opioidCodeineC18H21NO3Also an opioidDihydrocodeineC18H23NO3
More related molecules
Sources and notes
  • A group apartfrom sourceMoleculeFinder comparison captions
  • Compared side by sidefrom sourceMoleculeFinder comparison notesA molecule we compare it with on its own page.
  • The same kind of moleculefrom sourceMoleculeFinder curated groupsA structural neighbour in the same family or type group; the line names the group in its own words.
  • Similar in shapecomputedRDKit Morgan/TanimotoNeighbours by structural fingerprint; the sentence names the chemical groups the two share.
  • The drawingscomputedPubChem structures, drawn by RDKit