SHEET /m/naltrexone · PubChem CID 5360515 · CAS 16590-41-3 · REV 2026.07
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Naltrexone
from sourceC20H23NO4 · 341.4 g/mol
Celupan · Nalorex · Nemexin · Vivitrex
What is Naltrexone?
An opioid antagonist used in alcohol and opioid use disorder. It occupies the same receptors opioids use and blocks them for a day at a time. from source
CategoryPrescription medicine
Fig. 1 · 2D structure RDKit
SMILES
C1CC1CN2CC[C@]34[C@@H]5C(=O)CC[C@]3([C@H]2CC6=C4C(=C(C=C6)O)O5)OWhere you'll find it
Dispensed on prescription, not sold on a shelf. See the rest of the prescription medicine group.
Relative acute toxicity from source
Animal study data · LD50
- Reported LD50
- 1,450 mg/kg · low toxicity
- Species
- rat
- Route
- oral
An LD50 describes acute toxicity under experimental conditions and is not a safe or dangerous dose for a person.
Toxicity & hazards
Toxicity · LD50
1,450 mg/kg · low toxicity · LD50 rat oral from source
2 more reported values
- 1,490 mg/kgLD50 · oral · guinea pig
- 3,000 mg/kgLD50 · oral · monkey
DangerIrritantHealth hazardEnvironmentalH302, H312, H317, H332, H334, H341, H400from source
Keep roaming
Where Naltrexone leads
Relatedcomputed