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SHEET /m/codeine · PubChem CID 5284371 · CAS 76-57-3 · REV 2026.07

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Codeine

from source

C18H21NO3 · 299.4 g/mol

methylmorphine · morphine monomethyl ether · Codicept · Coducept

What is Codeine?

A mild opioid from the opium poppy, used for pain and cough. The body has to convert it into morphine for it to work at all. from source

CategoryPrescription medicine
Chemical familyAlcoholsAromaticsEthers
LeaderboardsBiggestDeadliest

Fig. 1 · 2D structure RDKit

SMILESCN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)OC)O[C@H]3[C@H](C=C4)O

Where you'll find it

Dispensed on prescription, not sold on a shelf. See the rest of the prescription medicine group.

Relative acute toxicity from source

Animal study data · LD50

Reported LD50
427 mg/kg · low toxicity
Species
rat
Route
oral

An LD50 describes acute toxicity under experimental conditions and is not a safe or dangerous dose for a person.

Toxicity & hazards

Toxicity · LD50

427 mg/kg · low toxicity · LD50 rat oral from source

3 more reported values
  • 75 mg/kgLD50 · iv · rat
  • 100 mg/kgLD50 · other · rat
  • 229 mg/kgLD50 · other · rat
DangerCorrosiveIrritantHealth hazardH302, H317, H318, H336, H362from source

Keep roaming

Where Codeine leads

Relatedcomputed
Morphine76% similarBoth carry an alcohol and an ether group.Hydrocodone55% similarBoth carry an ether group.Oxycodone43% similarBoth carry an alcohol and an ether group.Hydromorphone41% similarBoth carry an ether group.

Compare with

Codeine vs Tramadol

Sources & methodology

PubChem CID
5284371
Wikidata
Q174723
Structure
PubChem → RDKit
LD50
PubChem
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MoleculeFinder fingerprint similarity
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