moleculefinder

Lisinopril

C21H31N3O5405.5 g/mol Calculated

Also called Carace, Novatec, Prinivil and Qbrelis.

An ACE inhibitor used for high blood pressure and heart failure. Its lineage traces to a peptide in Brazilian pit viper venom.

Sources and notes
  • The introductionfrom sourceMoleculeFinder curated
  • Other namesfrom sourcePubChem / Wikidata
  • Formula and weightcomputedPubChem
  • 2D drawingcomputedPubChem structure, drawn by RDKit
  • 3D modelfrom sourcePubChem 3D conformerLoaded after the page has painted, and on a phone only when you ask for it; the 2D drawing shows until it arrives.

Where you encounter it

Dispensed on prescription, not sold on a shelf. Lisinopril on the product labels we hold.

Medicines

ZestrilAdded by the makerActive ingredient

Every product and list we hold

Sources and notes
  • The product labels and their strengthsfrom sourceDailyMed (FDA label)Each label lists the molecule as an ingredient, and an active ingredient at the strength shown.
  • How it gets therefrom sourceMoleculeFinder curatedEach mark is set by hand on our lists, never inferred; a label's ingredient is added by the maker. A row with no mark data says Not marked.
  • The line abovefrom sourceMoleculeFinder curatedFrom the group the molecule belongs to.

Explore its structure

Choose a part to light it up.

A carbon carrying both a C=O and an O-H, written COOH. In water it gives up that hydrogen, which is what makes the molecule an acid.

From: standard chemistry.

Sources and notes
  • The drawingcomputedPubChem structure, drawn by RDKitThe page's one shipped drawing, with the chosen part lit in amber under it.
  • The partscomputedFound by ruleEach part is found by a chemical pattern, never picked by hand atom by atom; its words say where they come from.

Compare a related molecule

Lisinopril

Losartan

Lisinopril blocks the enzyme that makes angiotensin II and losartan blocks its receptor, which is why lisinopril can cause a dry cough and losartan does not.

Lisinopril vs Losartan, side by side

Also compared

Sources and notes
  • The sentencefrom sourceMoleculeFinder comparison notesThe pair's answer line.
  • The two drawingscomputedPubChem structures, drawn by RDKitThe two drawings side by side.

Properties and sources

Calculated by PubChem

Molecular formula
C21H31N3O5
Molecular weight
405.5 g/mol
XLogP3octanol/water, log units
−2.9
Polar surface areatopological
133 Ų
H-bond donors
4
H-bond acceptors
7
Rotatable bonds
12
Complexity
550

Reported Hazard label (GHS), ECHA via PubChem

Danger Irritant pictogram (GHS07) and Health hazard pictogram (GHS08); hazard statements H315, H319, H360, H361, H362, H373

Reported Licence

The US Food and Drug Administration licenses Lisinopril for human use (NDA 019777, authorized May 19, 1988). Drugs@FDA

Groups it belongs to

Category
Prescription medicine
Family
Blood-pressure medicines
Chemical groups
Carboxylic Acids, Amines, Aromatics, Amides
Elements
Nitrogen
Hazard classes
Irritant, Health hazard, GHS Danger
SMILESC1C[C@H](N(C1)C(=O)[C@H](CCCCN)N[C@@H](CCC2=CC=CC=C2)C(=O)O)C(=O)O

PubChem CID 5362119 · Wikidata Q412208 · InChIKey RLAWWYSOJDYHDC-BZSNNMDCSA-N · Data refreshed

How MoleculeFinder sources and labels its data

Questions
What is Lisinopril?
An ACE inhibitor used for high blood pressure and heart failure. Its lineage traces to a peptide in Brazilian pit viper venom.
How toxic is Lisinopril?
Its GHS hazard label carries the signal word Danger and the hazard pictograms Irritant and Health hazard. from source
What kind of molecule is Lisinopril?
Lisinopril has the formula C21H31N3O5 and a molecular weight of 405.5 g/mol. MoleculeFinder files it under blood-pressure medicines, in the prescription medicine group. from sourcefrom sourcefrom sourcefrom source
Who licenses Lisinopril as a medicine?
The US Food and Drug Administration licenses Lisinopril for human use (NDA 019777, authorized May 19, 1988). from source
Sources and notes
  • Calculated valuescomputedPubChemComputed from the structure, so no laboratory conditions apply; complexity is PubChem's own structural score.
  • Hazard labelfrom sourceECHA via PubChemThe label combines these classifications.
  • ECHAfrom sourceAttributionSource: European Chemicals Agency, echa.europa.eu.
  • Licencefrom sourceDrugs@FDARead 2026-10-21.
  • Data refreshedfrom sourceMoleculeFinder2026-11-09

Keep exploring

Compared side by side with lisinoprilLosartanC22H23ClN6OCompared side by side with lisinoprilAmlodipineC20H25ClN2O5Compared side by side with lisinoprilRamiprilC23H32N2O5Both carry a carboxylic acid, an amide and an amine group.BradykininC50H73N15O11
Sources and notes
  • Compared side by sidefrom sourceMoleculeFinder comparison notesA molecule we compare it with on its own page.
  • Similar in shapecomputedRDKit Morgan/TanimotoNeighbours by structural fingerprint; the sentence names the chemical groups the two share.
  • The drawingscomputedPubChem structures, drawn by RDKit