moleculefinder

Losartan

C22H23ClN6O422.9 g/mol Calculated

Also called allisartan, Angizaar, Lortaan and Lozap.

An angiotensin receptor blocker sold as Cozaar, used for high blood pressure and to protect the kidneys in diabetes.

Sources and notes
  • The introductionfrom sourceMoleculeFinder curated
  • Other namesfrom sourcePubChem / Wikidata
  • Formula and weightcomputedPubChem
  • 2D drawingcomputedPubChem structure, drawn by RDKit
  • 3D modelfrom sourcePubChem 3D conformerLoaded after the page has painted, and on a phone only when you ask for it; the 2D drawing shows until it arrives.

Where you encounter it

Dispensed on prescription, not sold on a shelf. Losartan on the product labels we hold.

Medicines

CozaarAdded by the makerActive ingredient

Every product and list we hold

Sources and notes
  • The product labels and their strengthsfrom sourceDailyMed (FDA label)Each label lists the molecule as an ingredient, and an active ingredient at the strength shown.
  • How it gets therefrom sourceMoleculeFinder curatedEach mark is set by hand on our lists, never inferred; a label's ingredient is added by the maker. A row with no mark data says Not marked.
  • The line abovefrom sourceMoleculeFinder curatedFrom the group the molecule belongs to.

Explore its structure

Choose a part to light it up.

An O-H on a carbon that is not part of an aromatic ring, the group that makes a molecule an alcohol. It both gives and accepts hydrogen bonds, which helps the molecule mix with water.

From: standard chemistry.

Sources and notes
  • The drawingcomputedPubChem structure, drawn by RDKitThe page's one shipped drawing, with the chosen part lit in amber under it.
  • The partscomputedFound by ruleEach part is found by a chemical pattern, never picked by hand atom by atom; its words say where they come from.

Compare a related molecule

Lisinopril

Losartan

Lisinopril blocks the enzyme that makes angiotensin II and losartan blocks its receptor, which is why lisinopril can cause a dry cough and losartan does not.

Lisinopril vs Losartan, side by side

Also compared

Sources and notes
  • The sentencefrom sourceMoleculeFinder comparison notesThe pair's answer line.
  • The two drawingscomputedPubChem structures, drawn by RDKitThe two drawings side by side.

Properties and sources

Calculated by PubChem

Molecular formula
C22H23ClN6O
Molecular weight
422.9 g/mol
XLogP3octanol/water, log units
4.3
Polar surface areatopological
92.5 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
8
Complexity
520

Reported Hazard label (GHS), ECHA via PubChem

Danger Irritant pictogram (GHS07) and Health hazard pictogram (GHS08); hazard statements H315, H317, H319, H335, H360, H362, H413

Reported Licence

The US Food and Drug Administration licenses Losartan for human use (NDA 020386, authorized April 14, 1995), as Cozaar. Drugs@FDA

Groups it belongs to

Category
Prescription medicine
Family
Blood-pressure medicines
Chemical groups
Alcohols, Aromatics, Halogenated
Elements
Chlorine, Nitrogen
Hazard classes
Irritant, Health hazard, GHS Danger
SMILESCCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)CO)Cl

PubChem CID 3961 · Wikidata Q410074 · InChIKey PSIFNNKUMBGKDQ-UHFFFAOYSA-N · Data refreshed

How MoleculeFinder sources and labels its data

Questions
What is Losartan?
An angiotensin receptor blocker sold as Cozaar, used for high blood pressure and to protect the kidneys in diabetes.
How toxic is Losartan?
Its GHS hazard label carries the signal word Danger and the hazard pictograms Irritant and Health hazard. from source
What kind of molecule is Losartan?
Losartan has the formula C22H23ClN6O and a molecular weight of 422.9 g/mol. MoleculeFinder files it under blood-pressure medicines, in the prescription medicine group. from sourcefrom sourcefrom sourcefrom source
Who licenses Losartan as a medicine?
The US Food and Drug Administration licenses Losartan for human use (NDA 020386, authorized April 14, 1995), as Cozaar. from source
Sources and notes
  • Calculated valuescomputedPubChemComputed from the structure, so no laboratory conditions apply; complexity is PubChem's own structural score.
  • Hazard labelfrom sourceECHA via PubChemThe label combines these classifications.
  • ECHAfrom sourceAttributionSource: European Chemicals Agency, echa.europa.eu.
  • Licencefrom sourceDrugs@FDARead 2026-10-21.
  • Data refreshedfrom sourceMoleculeFinder2026-11-09

Keep exploring

Compared side by side with losartanLisinoprilC21H31N3O5Compared side by side with losartanValsartanC24H29N5O3Also a blood-pressure medicineOlmesartanC24H26N6O3Also a blood-pressure medicineCandesartanC24H20N6O3
Sources and notes
  • Compared side by sidefrom sourceMoleculeFinder comparison notesA molecule we compare it with on its own page.
  • The same kind of moleculefrom sourceMoleculeFinder curated groupsA structural neighbour in the same family or type group; the line names the group in its own words.
  • The drawingscomputedPubChem structures, drawn by RDKit