SHEET /m/vanillin · PubChem CID 1183 · CAS 121-33-5 · REV 2026.07
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Vanillin from source
C8H8O3 · 152.15 g/mol
4-Hydroxy-3-methoxybenzaldehyde · Vanillic aldehyde · Vanillaldehyde · p-Vanillin
chemical compound
CategoryFood & flavor
Chemical familyAromatics
Fig. 1 · 2D structure RDKit
COC1=C(C=CC(=C1)C=O)O
Where you'll find it
Not yet mapped to everyday foods or products.
The dose makes the poison inferred
A reported rat oral LD50 for Vanillin is 1,580 mg/kg, the dose lethal to half the animals tested. Scaled by body mass alone:
110.6 g
a median lethal dose scaled to 154 lb (110,600 mg)
“The dose makes the poison” is a cross-species estimate shown as neutral science, not a threshold anyone should act on. Real toxicity depends on the person, not body mass alone.
Toxicity & hazards
Toxicity · LD50
1,580 mg/kg · low toxicity · LD50 rat oral from source
The dose lens above scales this to a body weight.
3 more reported values
- 475 mg/kgLD50 · other · mouse
- 1,160 mg/kgLD50 · other · rat
- 1,500 mg/kgLD50 · other · rat
WarningIrritantEnvironmentalH302, H317, H319, H320, H402, H411, H412from source
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