SHEET /m/eugenol · PubChem CID 3314 · CAS 97-53-0 · REV 2026.07
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Eugenol
from sourceC10H12O2 · 164.2 g/mol
p-Allylguaiacol · Eugenic acid · Caryophyllic acid · Allylguaiacol
What is Eugenol?
The smell and numbing bite of clove. Dentists have used clove oil on toothache for centuries because of it. from source
CategoryFood & flavor
Fig. 1 · 2D structure RDKit
SMILES
COC1=C(C=CC(=C1)CC=C)OThe dose makes the poison inferred
A reported rat oral LD50 for Eugenol is 1,930 mg/kg, the dose lethal to half the animals tested. Scaled by body mass alone:
135.1 g
a median lethal dose scaled to 154 lb (135,100 mg)
“The dose makes the poison” is a cross-species estimate shown as neutral science, not a threshold anyone should act on. Real toxicity depends on the person, not body mass alone.
Toxicity & hazards
Toxicity · LD50
1,930 mg/kg · low toxicity · LD50 rat oral from source
The dose lens above scales this to a body weight.
3 more reported values
- 2,130 mg/kgLD50 · oral · guinea pig
- 500 mg/kgLD50 · other · mouse
- 1,109 mg/kgLD50 · other · mouse
WarningIrritantHealth hazardH302, H315, H317, H319, H336, H351, H401, H412from source
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Where Eugenol leads
Relatedcomputed
Zingerone53% similarBoth carry a phenol and an ether group.Vanillin47% similarBoth carry a phenol and an ether group.Myristicin45% similarBoth carry an ether group.Curcumin44% similarBoth carry a phenol and an ether group.Shogaol44% similarBoth carry a phenol and an ether group.Nonivamide43% similarBoth carry a phenol and an ether group.