SHEET /m/thiamine · PubChem CID 1130 · REV 2026.07
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Thiamine from source
C12H17N4OS+ · 265.36 g/mol
thiamin · vitamin B1 · Aneurin · Antiberiberi factor
chemical compound
CategoryNutrient
TypeVitamin
Fig. 1 · 2D structure RDKit
CC1=C(SC=[N+]1CC2=CN=C(N=C2N)C)CCO
Where you'll find it
Not yet mapped to everyday foods or products.
The dose makes the poison inferred
A reported rat oral LD50 for Thiamine is 3,710 mg/kg, the dose lethal to half the animals tested. Scaled by body mass alone:
259.7 g
a median lethal dose scaled to 154 lb (259,700 mg)
“The dose makes the poison” is a cross-species estimate shown as neutral science, not a threshold anyone should act on. Real toxicity depends on the person, not body mass alone.
Toxicity & hazards
Toxicity · LD50
3,710 mg/kg · very low toxicity · LD50 rat oral from source
The dose lens above scales this to a body weight.
5 more reported values
- 8,224 mg/kgLD50 · oral · mouse
- 83 mg/kgLD50 · iv · mouse
- 188 mg/kgLD50 · iv · rat
- 301 mg/kgLD50 · other · mouse
- 560 mg/kgLD50 · other · rat