Nicotine from source

C10H14N2 · 162.23 g/mol

L-Nicotine · (-)-Nicotine · (S)-Nicotine · (S)-3-(1-methylpyrrolidin-2-yl)pyridine

a mild chemical stimulant naturally found in some plants

CategoryPlant

TypeStimulant

LeaderboardsBiggest Deadliest

Fig. 1 · 2D structure RDKit

CN1CCC[C@H]1C2=CN=CC=C2

Where you'll find it

Not yet mapped to everyday foods or products.

Still in your system computed

Nicotine clears on a half-life of 2 h. Every 2 hours, half of what's left is gone. Put in what you had:

servings (2 mg)1hours ago0 h

2 mg left

100% of your 2 mg remains · back under one serving ≈ 0.8 h after your last

The dose makes the poison inferred

A reported mouse oral LD50 for Nicotine is 24 mg/kg, the dose lethal to half the animals tested. Scaled by body mass alone:

your weight154 lb

1.7 g ≈ 1,120 servings

a median lethal dose scaled to 154 lb (1,680 mg)

“The dose makes the poison” is a cross-species estimate shown as neutral science, not a threshold anyone should act on. Real toxicity depends on the person, not body mass alone.

Signature properties

Half-life2 hfrom source

Toxicity & hazards

Toxicity · LD50

24 mg/kg · highly toxic · LD50 mouse oral from source

The dose lens above scales this to a body weight.

7 more reported values

188 mg/kgLD50 · oral · rat
2.8 mg/kgLD50 · iv · rat
5.9 mg/kgLD50 · other · mouse
25 mg/kgLD50 · other · rat
30 mg/kgLD50 · other · rat
33.5 mg/kgLD50 · other · rat
140 mg/kgLD50 · dermal · rat

DangerCorrosiveToxicIrritantHealth hazardEnvironmentalH300, H301, H310, H315, H318, H330, H335, H341, H361, H370, H400, H401, H411from source

Nicotine is the stimulant that makes tobacco addictive, and one of the fastest-clearing drugs people use: its half-life is only about two hours, part of why cravings return so quickly. In the plant it is a natural pesticide.