SHEET /m/imipramine · PubChem CID 3696 · CAS 50-49-7 · REV 2026.07
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Imipramine
from sourceC19H24N2 · 280.4 g/mol
melipramine · Antideprin · Berkomine · Dimipressin
What is Imipramine?
The first tricyclic antidepressant, sold as Tofranil, found in the 1950s during a search for a new antipsychotic. It is also used for bedwetting in children. from source
CategoryPrescription medicine
Chemical familyAromatics
Fig. 1 · 2D structure RDKit
SMILES
CN(C)CCCN1C2=CC=CC=C2CCC3=CC=CC=C31Where you'll find it
Dispensed on prescription, not sold on a shelf. See the rest of the prescription medicine group.
Relative acute toxicity from source
Animal study data · LD50
- Reported LD50
- 250 mg/kg · moderately toxic
- Species
- rat
- Route
- oral
An LD50 describes acute toxicity under experimental conditions and is not a safe or dangerous dose for a person.
Toxicity & hazards
Toxicity · LD50
250 mg/kg · moderately toxic · LD50 rat oral from source
3 more reported values
- 15.9 mg/kgLD50 · iv · rat
- 79 mg/kgLD50 · other · rat
- 250 mg/kgLD50 · other · rat
WarningIrritantEnvironmentalH302, H400from source
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