SHEET /m/chlorpromazine · PubChem CID 2726 · CAS 50-53-3 · REV 2026.07

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Chlorpromazine

from source

C17H19ClN2S · 318.9 g/mol

CPZ · Aminazine · Chlorderazin · Chlorpromados

What is Chlorpromazine?

The first antipsychotic, introduced in 1952, which changed how psychiatric illness was treated and emptied a generation of asylums. from source

CategoryPrescription medicine

Chemical familyAromatics Halogenated

LeaderboardsBiggest Deadliest

Fig. 1 · 2D structure RDKit

SMILESCN(C)CCCN1C2=CC=CC=C2SC3=C1C=C(C=C3)Cl

Where you'll find it

Dispensed on prescription, not sold on a shelf. See the rest of the prescription medicine group.

Relative acute toxicity from source

Animal study data · LD50

Reported LD50: 142 mg/kg · moderately toxic
Species: rat
Route: oral

An LD50 describes acute toxicity under experimental conditions and is not a safe or dangerous dose for a person.

Toxicity & hazards

Toxicity · LD50

142 mg/kg · moderately toxic · LD50 rat oral from source

3 more reported values

225 mg/kgLD50 · oral · rat
58 mg/kgLD50 · other · rat
75 mg/kgLD50 · other · rat

DangerToxicEnvironmentalH301, H317, H331, H362, H400, H410from source

Keep roaming

Where Chlorpromazine leads

Relatedcomputed

Prochlorperazine65% similarBoth carry an aromatic ring and a halogen atom.Clomipramine62% similarBoth carry an aromatic ring and a halogen atom.Promethazine43% similarBoth carry an aromatic ring.

Sources & methodology

PubChem CID: 2726
Wikidata: Q407972
Structure: PubChem → RDKit
LD50: PubChem
Similar molecules: MoleculeFinder fingerprint similarity
Data refreshed: September 13, 2026

How MoleculeFinder sources and labels its data