Clomipramine
Also called chlorimipramine and monochlorimipramine.
A tricyclic antidepressant used chiefly for OCD, and in 1989 the first medicine the FDA approved for it.
Sources and notes
- The introductionfrom sourceMoleculeFinder curated
- Other namesfrom sourceWikidataIts English label and aliases on Wikidata.
- Formula and weightcomputedPubChem
- 2D drawingcomputedPubChem structure, drawn by RDKit
- 3D modelfrom sourcePubChem 3D conformerLoaded after the page has painted, and on a phone only when you ask for it; the 2D drawing shows until it arrives.
Where you encounter it
Dispensed on prescription, not sold on a shelf. Clomipramine on the product labels we hold.
Medicines
Every product and list we hold
Sources and notes
- The product labels and their strengthsfrom sourceDailyMed (FDA label)Each label lists the molecule as an ingredient, and an active ingredient at the strength shown.
- How it gets therefrom sourceMoleculeFinder curatedEach mark is set by hand on our lists, never inferred; a label's ingredient is added by the maker. A row with no mark data says Not marked.
- The line abovefrom sourceMoleculeFinder curatedFrom the group the molecule belongs to.
Explore its structure
Choose a part to light it up.
A nitrogen bonded to three carbons, with no hydrogen of its own. Its spare pair of electrons can still pick up a hydrogen ion, so a tertiary amine is a base.
From: standard chemistry.
Fluorine, chlorine, bromine or iodine bonded to carbon. Each pulls electrons toward itself, and each is larger than the hydrogen the carbon would otherwise carry.
From: standard chemistry.
Rings joined where they share atoms, or a single ring standing alone. Atoms in a ring are held in place, so this part keeps its shape while chains around it can bend.
From: standard chemistry.
Sources and notes
- The drawingcomputedPubChem structure, drawn by RDKitThe page's one shipped drawing, with the chosen part lit in amber under it.
- The partscomputedFound by ruleEach part is found by a chemical pattern, never picked by hand atom by atom; its words say where they come from.
Properties and sources
Calculated by PubChem
- Molecular formula
- C19H23ClN2
- Molecular weight
- 314.9 g/mol
- XLogP3octanol/water, log units
- 5.2
- Polar surface areatopological
- 6.5 Ų
- H-bond donors
- 0
- H-bond acceptors
- 2
- Rotatable bonds
- 4
- Complexity
- 346
Reported Hazard label (GHS), ECHA via PubChem
Warning Irritant pictogram (GHS07); hazard statements H302
Reported Licence
The US Food and Drug Administration licenses Clomipramine for human use (NDA 019906, authorized December 29, 1989), as Anafranil. Drugs@FDA
Groups it belongs to
- Category
- Prescription medicine
- Chemical groups
- Aromatics, Halogenated
- Hazard classes
- Irritant, GHS Warning
CN(C)CCCN1C2=CC=CC=C2CCC3=C1C=C(C=C3)ClPubChem CID 2801 · Wikidata Q58713 · InChIKey GDLIGKIOYRNHDA-UHFFFAOYSA-N · Data refreshed
Questions
- What is Clomipramine?
- A tricyclic antidepressant used chiefly for OCD, and in 1989 the first medicine the FDA approved for it.
- How toxic is Clomipramine?
- Its GHS hazard label carries the signal word Warning and the hazard pictogram Irritant. from source
- What kind of molecule is Clomipramine?
- Clomipramine has the formula C19H23ClN2 and a molecular weight of 314.9 g/mol. MoleculeFinder files it under tricyclic antidepressants, in the prescription medicine group. from sourcefrom sourcefrom sourcefrom source
- What else is Clomipramine called?
- Clomipramine is also called chlorimipramine and monochlorimipramine. from source
- Who licenses Clomipramine as a medicine?
- The US Food and Drug Administration licenses Clomipramine for human use (NDA 019906, authorized December 29, 1989), as Anafranil. from source
Sources and notes
- Calculated valuescomputedPubChemComputed from the structure, so no laboratory conditions apply; complexity is PubChem's own structural score.
- Hazard labelfrom sourceECHA via PubChemThe label combines these classifications.
- ECHAfrom sourceAttributionSource: European Chemicals Agency, echa.europa.eu.
- Licencefrom sourceDrugs@FDARead 2026-10-21.
- Data refreshedfrom sourceMoleculeFinder2026-11-09
Keep exploring
Sources and notes
- The same kind of moleculefrom sourceMoleculeFinder curated groupsA structural neighbour in the same family or type group; the line names the group in its own words.
- Similar in shapecomputedRDKit Morgan/TanimotoNeighbours by structural fingerprint; the sentence names the chemical groups the two share.
- The drawingscomputedPubChem structures, drawn by RDKit