SHEET /m/promethazine · PubChem CID 4927 · CAS 60-87-7 · REV 2026.07
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Promethazine
from sourceC17H20N2S · 284.4 g/mol
proazamine · Dimapp · Diphergan · Fargan
What is Promethazine?
A sedating antihistamine used for allergy, motion sickness, nausea and, in combination syrups, cough. from source
CategoryPrescription medicine
Chemical familyAromatics
Fig. 1 · 2D structure RDKit
SMILES
CC(CN1C2=CC=CC=C2SC3=CC=CC=C31)N(C)CWhere you'll find it
Dispensed on prescription, not sold on a shelf. See the rest of the prescription medicine group.
Relative acute toxicity from source
Animal study data · LD50
- Reported LD50
- 580 mg/kg · low toxicity
- Species
- rabbit
- Route
- oral
An LD50 describes acute toxicity under experimental conditions and is not a safe or dangerous dose for a person.
Toxicity & hazards
Toxicity · LD50
580 mg/kg · low toxicity · LD50 rabbit oral from source
3 more reported values
- 19 mg/kgLD50 · iv · rabbit
- 40 mg/kgLD50 · iv · mouse
- 175 mg/kgLD50 · other · mouse
DangerCorrosiveIrritantEnvironmentalH302, H317, H318, H319, H410, H411from source
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Where Promethazine leads
Relatedcomputed