SHEET /m/ibuprofen · PubChem CID 3672 · CAS 58560-75-1 · REV 2026.07
Ibuprofen
from sourceC13H18O2 · 206.28 g/mol
p-isobutylhydratropate · Advil · Anflagen · Brufen
Also sold as Advil, Motrin, Nurofen from source
What is Ibuprofen?
The anti-inflammatory painkiller sold as Advil and Motrin, one of the handful of drugs most households keep in a cabinet. from source
Fig. 1 · 2D structure RDKit
CC(C)CC1=CC=C(C=C1)C(C)C(=O)OWhere you'll find it
Curated by MoleculeFinder from source
Still in the system computed
For a typical adult, Ibuprofen clears on a half-life of about 2 h: every 2 hours, half of what is left is gone. Try an amount:
An illustration of half-life, not a prediction of anyone's level.
Relative acute toxicity from source
Animal study data · LD50
- Reported LD50
- 636 mg/kg · low toxicity
- Species
- rat
- Route
- oral
An LD50 describes acute toxicity under experimental conditions and is not a safe or dangerous dose for a person.
Signature properties
Toxicity & hazards
Toxicity · LD50
636 mg/kg · low toxicity · LD50 rat oral from source
4 more reported values
- 1,255 mg/kgLD50 · oral · mouse
- 530 mg/kgLD50 · other · rat
- 626 mg/kgLD50 · other · rat
- 740 mg/kgLD50 · other · rat
Keep roaming
Where Ibuprofen leads
Compare with
Ibuprofen is the everyday anti-inflammatory, blocking the COX enzymes that build the prostaglandins behind pain, fever, and swelling. It clears in about two hours, which is why the label says to redose every four to six.