SHEET /m/ibuprofen · PubChem CID 3672 · CAS 58560-75-1 · REV 2026.07
Ibuprofen from source
C13H18O2 · 206.28 g/mol
IBUPROFEN, (+-)- · 2-(4-Isobutylphenyl)propanoic acid · Motrin · Brufen
Also sold as Advil, Motrin, Nurofen from source
chemical compound
Fig. 1 · 2D structure RDKit
CC(C)CC1=CC=C(C=C1)C(C)C(=O)O
Where you'll find it
Not yet mapped to everyday foods or products.
Still in your system computed
Ibuprofen clears on a half-life of 2 h. Every 2 hours, half of what's left is gone. Put in what you had:
The dose makes the poison inferred
A reported rat oral LD50 for Ibuprofen is 636 mg/kg, the dose lethal to half the animals tested. Scaled by body mass alone:
“The dose makes the poison” is a cross-species estimate shown as neutral science, not a threshold anyone should act on. Real toxicity depends on the person, not body mass alone.
Signature properties
Toxicity & hazards
Toxicity · LD50
636 mg/kg · low toxicity · LD50 rat oral from source
The dose lens above scales this to a body weight.
3 more reported values
- 530 mg/kgLD50 · other · rat
- 626 mg/kgLD50 · other · rat
- 740 mg/kgLD50 · other · rat
Keep roaming
Where Ibuprofen leads
Ibuprofen is the everyday anti-inflammatory, blocking the COX enzymes that build the prostaglandins behind pain, fever, and swelling. It clears in about two hours, which is why the label says to redose every four to six.