moleculefinder

SHEET /m/ibuprofen · PubChem CID 3672 · CAS 58560-75-1 · REV 2026.07

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Ibuprofen from source

C13H18O2 · 206.28 g/mol

IBUPROFEN, (+-)- · 2-(4-Isobutylphenyl)propanoic acid · Motrin · Brufen

Also sold as Advil, Motrin, Nurofen from source

chemical compound

CategoryOTC medicine
LeaderboardsBiggestDeadliest

Fig. 1 · 2D structure RDKit

CC(C)CC1=CC=C(C=C1)C(C)C(=O)O

Where you'll find it

Not yet mapped to everyday foods or products.

Still in your system computed

Ibuprofen clears on a half-life of 2 h. Every 2 hours, half of what's left is gone. Put in what you had:

200 mg left
100% of your 200 mg remains

The dose makes the poison inferred

A reported rat oral LD50 for Ibuprofen is 636 mg/kg, the dose lethal to half the animals tested. Scaled by body mass alone:

44.5 g223 servings
a median lethal dose scaled to 154 lb (44,520 mg)

“The dose makes the poison” is a cross-species estimate shown as neutral science, not a threshold anyone should act on. Real toxicity depends on the person, not body mass alone.

Signature properties

Half-life2 hfrom source

Toxicity & hazards

Toxicity · LD50

636 mg/kg · low toxicity · LD50 rat oral from source

The dose lens above scales this to a body weight.

3 more reported values
  • 530 mg/kgLD50 · other · rat
  • 626 mg/kgLD50 · other · rat
  • 740 mg/kgLD50 · other · rat
DangerIrritantHealth hazardEnvironmentalH302, H319, H335, H360, H361, H362, H371, H373, H411from source

Keep roaming

Where Ibuprofen leads

Ibuprofen is the everyday anti-inflammatory, blocking the COX enzymes that build the prostaglandins behind pain, fever, and swelling. It clears in about two hours, which is why the label says to redose every four to six.