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SHEET /m/acetaminophen · PubChem CID 1983 · CAS 103-90-2 · REV 2026.07

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Acetaminophen

from source

C8H9NO2 · 151.16 g/mol

paracetamol · p-acetylaminophenol · p-hydroxyacetanilide · p-acetamidophenol

Also sold as Tylenol from source

What is Acetaminophen?

The pain and fever reliever sold as Tylenol and Panadol, and the most-visited page on MoleculeFinder. Outside the US it is usually called paracetamol. from source

CategoryOTC medicine
Chemical familyAromaticsAmidesPhenols
LeaderboardsBiggestDeadliest

Fig. 1 · 2D structure RDKit

SMILESCC(=O)NC1=CC=C(C=C1)O

Where you'll find it

Curated by MoleculeFinder from source

Still in the system computed

For a typical adult, Acetaminophen clears on a half-life of about 2 h: every 2 hours, half of what is left is gone. Try an amount:

500 mg left
100% of the 500 mg remains

An illustration of half-life, not a prediction of anyone's level.

Relative acute toxicity from source

Animal study data · LD50

Reported LD50
1,944 mg/kg · low toxicity
Species
rat
Route
oral

An LD50 describes acute toxicity under experimental conditions and is not a safe or dangerous dose for a person.

Signature properties

Half-life2 hfrom source

Toxicity & hazards

Toxicity · LD50

1,944 mg/kg · low toxicity · LD50 rat oral from source

5 more reported values
  • 338 mg/kgLD50 · oral · mouse
  • 2,400 mg/kgLD50 · oral · rat
  • 310 mg/kgLD50 · other · mouse
  • 367 mg/kgLD50 · other · mouse
  • 1,205 mg/kgLD50 · other · rat
DangerIrritantHealth hazardEnvironmentalH302, H315, H319, H335, H341, H370, H371, H372, H373, H401, H411, H412from source

Keep roaming

Where Acetaminophen leads

Compare with

Acetaminophen, sold as Tylenol or paracetamol, is the most common drug in the medicine cabinet and, in overdose, the leading cause of acute liver failure. It eases pain and fever without the stomach irritation of the NSAIDs, but its safety margin is narrower than most people assume.

Sources & methodology

PubChem CID
1983
Wikidata
Q57055
Structure
PubChem → RDKit
LD50
PubChem
Half-life
MoleculeFinder curated
Similar molecules
MoleculeFinder fingerprint similarity
Everyday relationships
MoleculeFinder editorial curation
Data refreshed

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