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SHEET /m/acetaminophen · PubChem CID 1983 · CAS 103-90-2 · REV 2026.07

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Acetaminophen from source

C8H9NO2 · 151.16 g/mol

Paracetamol · 4-Acetamidophenol · N-(4-Hydroxyphenyl)acetamide · Tylenol

Also sold as Tylenol from source

chemical compound with antipyretic and pain relieving properties

CategoryOTC medicine
Chemical familyAromatics
LeaderboardsBiggestDeadliest

Fig. 1 · 2D structure RDKit

CC(=O)NC1=CC=C(C=C1)O

Where you'll find it

Not yet mapped to everyday foods or products.

Still in your system computed

Acetaminophen clears on a half-life of 2 h. Every 2 hours, half of what's left is gone. Put in what you had:

500 mg left
100% of your 500 mg remains

The dose makes the poison inferred

A reported mouse oral LD50 for Acetaminophen is 338 mg/kg, the dose lethal to half the animals tested. Scaled by body mass alone:

23.7 g47 servings
a median lethal dose scaled to 154 lb (23,660 mg)

“The dose makes the poison” is a cross-species estimate shown as neutral science, not a threshold anyone should act on. Real toxicity depends on the person, not body mass alone.

Signature properties

Half-life2 hfrom source

Toxicity & hazards

Toxicity · LD50

338 mg/kg · low toxicity · LD50 mouse oral from source

The dose lens above scales this to a body weight.

5 more reported values
  • 1,944 mg/kgLD50 · oral · rat
  • 2,400 mg/kgLD50 · oral · rat
  • 310 mg/kgLD50 · other · mouse
  • 367 mg/kgLD50 · other · mouse
  • 1,205 mg/kgLD50 · other · rat
DangerIrritantHealth hazardEnvironmentalH302, H315, H319, H335, H341, H370, H371, H372, H373, H401, H411, H412from source

Keep roaming

Where Acetaminophen leads

Acetaminophen, sold as Tylenol or paracetamol, is the most common drug in the medicine cabinet and, in overdose, the leading cause of acute liver failure. It eases pain and fever without the stomach irritation of the NSAIDs, but its safety margin is narrower than most people assume.