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SHEET /m/safrole · PubChem CID 5144 · CAS 94-59-7 · REV 2026.07

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Safrole

from source

C10H10O2 · 162.18 g/mol

shikimole · shikimol · Shikomol

What is Safrole?

The root beer and sassafras aroma, banned as a food additive in 1960. It is also a precursor to MDMA, so its sale is watched. from source

CategoryPlant
Chemical familyAromaticsEthers
LeaderboardsBiggestDeadliest

Fig. 1 · 2D structure RDKit

SMILESC=CCC1=CC2=C(C=C1)OCO2

Relative acute toxicity from source

Animal study data · LD50

Reported LD50
1,950 mg/kg · low toxicity
Species
rat
Route
oral

An LD50 describes acute toxicity under experimental conditions and is not a safe or dangerous dose for a person.

Toxicity & hazards

Toxicity · LD50

1,950 mg/kg · low toxicity · LD50 rat oral from source

3 more reported values
  • 2,350 mg/kgLD50 · oral · mouse
  • 1,020 mg/kgLD50 · other · mouse
  • 5,000 mg/kgLD50 · dermal · rabbit
DangerIrritantHealth hazardH302, H315, H341, H350, H351, H371, H373from source

Keep roaming

Where Safrole leads

Sources & methodology

PubChem CID
5144
Wikidata
Q412424
Structure
PubChem → RDKit
LD50
PubChem
Similar molecules
MoleculeFinder fingerprint similarity
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