Piperonal

from source

C8H6O3 · 150.13 g/mol

heliotropine · piperonylaldehyde · heliotropin · piperonyl aldehyde

What is Piperonal?

The smell of heliotrope and cherry-vanilla, used in perfume and in the cherry note of some flavourings. It is derived from the same skeleton as safrole. from source

CategoryScent & aroma

Chemical familyAromatics Aldehydes Ethers

LeaderboardsBiggest Deadliest

Fig. 1 · 2D structure RDKit

SMILESC1OC2=C(O1)C=C(C=C2)C=O

The dose makes the poison inferred

A reported rat oral LD50 for Piperonal is 2,700 mg/kg, the dose lethal to half the animals tested. Scaled by body mass alone:

your weight154 lb

189.0 g

a median lethal dose scaled to 154 lb (189,000 mg)

“The dose makes the poison” is a cross-species estimate shown as neutral science, not a threshold anyone should act on. Real toxicity depends on the person, not body mass alone.

Toxicity & hazards

Toxicity · LD50

2,700 mg/kg · very low toxicity · LD50 rat oral from source

The dose lens above scales this to a body weight.

1 more reported value

500 mg/kgLD50 · other · mouse

DangerToxicIrritantHealth hazardH301, H312, H315, H317, H330, H336, H351, H360, H370, H372, H402, H412from source

Keep roaming

Where Piperonal leads

Sources & methodology

PubChem CID: 8438
Wikidata: Q418985
Structure: PubChem → RDKit
LD50: PubChem
Similar molecules: MoleculeFinder fingerprint similarity
Data refreshed: October 19, 2026

How MoleculeFinder sources and labels its data