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SHEET /m/phenytoin · PubChem CID 1775 · CAS 57-41-0 · REV 2026.07

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Phenytoin

from source

C15H12N2O2 · 252.27 g/mol

diphenylhydantoin · Dihycon · Dihydantoin · Dilabid

What is Phenytoin?

An anticonvulsant sold as Dilantin, in use since 1938. It was the first seizure medicine found that did not also sedate. from source

Chemical familyAromaticsAmides
LeaderboardsBiggestDeadliest

Fig. 1 · 2D structure RDKit

SMILESC1=CC=C(C=C1)C2(C(=O)NC(=O)N2)C3=CC=CC=C3

Where you'll find it

Dispensed on prescription, not sold on a shelf. See the rest of the prescription medicine group.

Relative acute toxicity from source

Animal study data · LD50

Reported LD50
1,635 mg/kg · low toxicity
Species
rat
Route
oral

An LD50 describes acute toxicity under experimental conditions and is not a safe or dangerous dose for a person.

Toxicity & hazards

Toxicity · LD50

1,635 mg/kg · low toxicity · LD50 rat oral from source

4 more reported values
  • 150 mg/kgLD50 · oral · mouse
  • 100 mg/kgLD50 · other · mouse
  • 101 mg/kgLD50 · iv · rat
  • 110 mg/kgLD50 · other · mouse
DangerIrritantHealth hazardH302, H340, H350, H351, H360, H370, H372, H402, H412from source

Keep roaming

Where Phenytoin leads

Sources & methodology

PubChem CID
1775
Wikidata
Q410400
Structure
PubChem → RDKit
LD50
PubChem
Similar molecules
MoleculeFinder fingerprint similarity
Data refreshed

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