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SHEET /m/phenobarbital · PubChem CID 4763 · CAS 50-06-6 · REV 2026.07

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Phenobarbital

from source

C12H12N2O3 · 232.23 g/mol

phenylethylbarbiturate · luminal · phenobarbituric acid · phenobarbitone

What is Phenobarbital?

The oldest anticonvulsant still in wide use, more than a century old, and still on the WHO essential medicines list for seizures. from source

Chemical familyAromaticsAmides
LeaderboardsBiggestDeadliest

Fig. 1 · 2D structure RDKit

SMILESCCC1(C(=O)NC(=O)NC1=O)C2=CC=CC=C2

Where you'll find it

Dispensed on prescription, not sold on a shelf. See the rest of the prescription medicine group.

Relative acute toxicity from source

Animal study data · LD50

Reported LD50
660 mg/kg · low toxicity
Species
rat
Route
oral

An LD50 describes acute toxicity under experimental conditions and is not a safe or dangerous dose for a person.

Toxicity & hazards

Toxicity · LD50

660 mg/kg · low toxicity · LD50 rat oral from source

2 more reported values
  • 151 mg/kgLD50 · other · rat
  • 200 mg/kgLD50 · other · rat
DangerToxicIrritantHealth hazardH301, H317, H336, H340, H350, H351, H360, H361, H372, H373from source

Keep roaming

Where Phenobarbital leads

Sources & methodology

PubChem CID
4763
Wikidata
Q407241
Structure
PubChem → RDKit
LD50
PubChem
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MoleculeFinder fingerprint similarity
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