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SHEET /m/pentobarbital · PubChem CID 4737 · CAS 76-74-4 · REV 2026.07

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Pentobarbital

from source

C11H18N2O3 · 226.27 g/mol

pentobarbituric acid · pentobarbitone · Dorsital · Ethaminal

What is Pentobarbital?

A barbiturate once used for sedation and seizures, now mostly a veterinary anaesthetic and euthanasia agent. from source

Chemical familyAmides
LeaderboardsBiggestDeadliest

Fig. 1 · 2D structure RDKit

SMILESCCCC(C)C1(C(=O)NC(=O)NC1=O)CC

Where you'll find it

Dispensed on prescription, not sold on a shelf. See the rest of the prescription medicine group.

Relative acute toxicity from source

Animal study data · LD50

Reported LD50
118 mg/kg · moderately toxic
Species
rat
Route
oral

An LD50 describes acute toxicity under experimental conditions and is not a safe or dangerous dose for a person.

Toxicity & hazards

Toxicity · LD50

118 mg/kg · moderately toxic · LD50 rat oral from source

3 more reported values
  • 125 mg/kgLD50 · oral · rat
  • 108 mg/kgLD50 · other · rat
  • 144 mg/kgLD50 · other · rat
DangerToxicHealth hazardH301, H361from source

Keep roaming

Where Pentobarbital leads

Sources & methodology

PubChem CID
4737
Wikidata
Q409632
Structure
PubChem → RDKit
LD50
PubChem
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