SHEET /m/niacin · PubChem CID 938 · CAS 59-67-6 · REV 2026.07
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Nicotinic acid from source
C6H5NO2 · 123.11 g/mol
niacin · Pyridine-3-carboxylic acid · 3-pyridinecarboxylic acid · 3-Carboxypyridine
chemical compound: acid form of vitamin B3
CategoryNutrient
TypeVitamin
Chemical familyCarboxylic Acids
Fig. 1 · 2D structure RDKit
C1=CC(=CN=C1)C(=O)O
Where you'll find it
Not yet mapped to everyday foods or products.
The dose makes the poison inferred
A reported mouse oral LD50 for Nicotinic acid is 3,720 mg/kg, the dose lethal to half the animals tested. Scaled by body mass alone:
260.4 g
a median lethal dose scaled to 154 lb (260,400 mg)
“The dose makes the poison” is a cross-species estimate shown as neutral science, not a threshold anyone should act on. Real toxicity depends on the person, not body mass alone.
Toxicity & hazards
Toxicity · LD50
3,720 mg/kg · very low toxicity · LD50 mouse oral from source
The dose lens above scales this to a body weight.
4 more reported values
- 7,000 mg/kgLD50 · oral · rat
- 730 mg/kgLD50 · other · rat
- 3,500 mg/kgLD50 · other · mouse
- 5,000 mg/kgLD50 · other · rat
WarningIrritantH319, H402from source
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