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SHEET /m/nicotinamide · PubChem CID 936 · CAS 98-92-0 · REV 2026.07

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Nicotinamide from source

C6H6N2O · 122.12 g/mol

niacinamide · 3-Pyridinecarboxamide · pyridine-3-carboxamide · Nicotinic acid amide

chemical compound: amide form of vitamin B3

CategoryNutrient
LeaderboardsBiggestDeadliest

Fig. 1 · 2D structure RDKit

C1=CC(=CN=C1)C(=O)N

Where you'll find it

Not yet mapped to everyday foods or products.

The dose makes the poison inferred

A reported mouse oral LD50 for Nicotinamide is 2,500 mg/kg, the dose lethal to half the animals tested. Scaled by body mass alone:

175.0 g
a median lethal dose scaled to 154 lb (175,000 mg)

“The dose makes the poison” is a cross-species estimate shown as neutral science, not a threshold anyone should act on. Real toxicity depends on the person, not body mass alone.

Toxicity & hazards

Toxicity · LD50

2,500 mg/kg · very low toxicity · LD50 mouse oral from source

The dose lens above scales this to a body weight.

3 more reported values
  • 3,500 mg/kgLD50 · oral · rat
  • 1,680 mg/kgLD50 · other · rat
  • 2,050 mg/kgLD50 · other · mouse
WarningIrritantH315, H319, H335from source

Keep roaming

Where Nicotinamide leads