Methylphenidate

from source

C14H19NO2 · 233.31 g/mol

methyl phenidylacetate · MPH · Calocain · Daytrana

What is Methylphenidate?

The stimulant sold as Ritalin and Concerta, used for ADHD and narcolepsy. It shares the phenethylamine skeleton with the body's own messengers. from source

CategoryPrescription medicine

Chemical familyAmines Aromatics Esters

LeaderboardsBiggest Deadliest

Fig. 1 · 2D structure RDKit

SMILESCOC(=O)C(C1CCCCN1)C2=CC=CC=C2

Where you'll find it

Dispensed on prescription, not sold on a shelf. See the rest of the prescription medicine group.

Relative acute toxicity from source

Animal study data · LD50

Reported LD50: 190 mg/kg · moderately toxic
Species: mouse
Route: oral

An LD50 describes acute toxicity under experimental conditions and is not a safe or dangerous dose for a person.

Toxicity & hazards

Toxicity · LD50

190 mg/kg · moderately toxic · LD50 mouse oral from source

4 more reported values

32 mg/kgLD50 · other · mouse
41 mg/kgLD50 · iv · mouse
218 mg/kgLD50 · other · mouse
430 mg/kgLD50 · other · rat

DangerIrritantHealth hazardH302, H315, H319, H334, H341from source

Compare with

Methylphenidate vs Amphetamine

Sources & methodology

PubChem CID: 4158
Wikidata: Q422112
Structure: PubChem → RDKit
LD50: PubChem
Data refreshed: September 13, 2026

How MoleculeFinder sources and labels its data