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SHEET /vs/dexmethylphenidate-vs-methylphenidate · COMPARISON

Dexmethylphenidate vs Methylphenidate: what is the difference?

DexmethylphenidateC14H19NO2 MethylphenidateC14H19NO2

How they differ

from source

Dexmethylphenidate is the active half of methylphenidate, so the two share the formula C14H19NO2 and a weight of 233.3. The Ritalin molecule is a mix of two mirror-image forms, and nearly all of its effect on dopamine and norepinephrine comes from the d-threo form that Focalin isolates. Removing the inactive half changes how much is in a tablet, not how the active molecule works. Both are prescription stimulants for ADHD and controlled substances in the United States and the UK.

Side by side

 DexmethylphenidateMethylphenidate
FormulaC14H19NO2C14H19NO2
Molecular weight233.31 g/mol233.31 g/mol
FamilyStimulantsStimulants
Everyday groupPrescription medicinePrescription medicine
Functional groupsAmines, Aromatics, EstersAmines, Aromatics, Esters
GHS signal wordThe supplier-filed hazard label, not a statement about ordinary use.not recordedDanger
Oral LD50A single acute animal measure. It ranks nothing about human safety.not recorded190 mg/kg (oral, mouse)
CAS number40431-64-9113-45-1
PubChem CID1541014158

Structural similarity 1.00 of 1, computed as a Morgan fingerprint Tanimoto coefficient. It measures shape, not effect.

Common questions

What is the difference between Dexmethylphenidate and Methylphenidate?
Dexmethylphenidate is the active half of methylphenidate, so the two share the formula C14H19NO2 and a weight of 233.3. The Ritalin molecule is a mix of two mirror-image forms, and nearly all of its effect on dopamine and norepinephrine comes from the d-threo form that Focalin isolates. Removing the inactive half changes how much is in a tablet, not how the active molecule works.
Do Dexmethylphenidate and Methylphenidate have the same formula?
Yes. Both are C14H19NO2 at 233.31 g/mol. They are isomers: the same atoms arranged differently, which is why they behave differently despite weighing the same.

Read the full records: Dexmethylphenidate and Methylphenidate.