Amphetamine
Also called α-methylphenethylamine, β-aminopropylbenzene, β-phenylisopropylamine and beta-aminopropylbenzene.
The stimulant at the root of the whole class, used for ADHD and narcolepsy and sold as Adderall in a mixed-salt form. A single phenyl ring, a two-carbon chain, an amine.
Sources and notes
- The introductionfrom sourceMoleculeFinder curated
- Other namesfrom sourceWikidataIts English label and aliases on Wikidata.
- Formula and weightcomputedPubChem
- 2D drawingcomputedPubChem structure, drawn by RDKit
- 3D modelfrom sourcePubChem 3D conformerLoaded after the page has painted, and on a phone only when you ask for it; the 2D drawing shows until it arrives.
Where you encounter it
Dispensed on prescription, not sold on a shelf. Amphetamine on the product labels we hold.
Medicines
Every product and list we hold
Sources and notes
- The product labels and their strengthsfrom sourceDailyMed (FDA label)Each label lists the molecule as an ingredient, and an active ingredient at the strength shown.
- How it gets therefrom sourceMoleculeFinder curatedEach mark is set by hand on our lists, never inferred; a label's ingredient is added by the maker. A row with no mark data says Not marked.
- The line abovefrom sourceMoleculeFinder curatedFrom the group the molecule belongs to.
Explore its structure
Choose a part to light it up.
A nitrogen carrying one or two hydrogens. Its spare pair of electrons can pick up a hydrogen ion, so an amine is a base.
From: standard chemistry.
Six carbons in a flat hexagon, sharing their electrons evenly around the ring. It is stable, flat and oily, and it stacks readily against other flat rings.
From: standard chemistry.
Sources and notes
- The drawingcomputedPubChem structure, drawn by RDKitThe page's one shipped drawing, with the chosen part lit in amber under it.
- The partscomputedFound by ruleEach part is found by a chemical pattern, never picked by hand atom by atom; its words say where they come from.
Compare a related molecule
Methylphenidate
Amphetamine
Methylphenidate blocks dopamine reuptake, while amphetamine also pushes stored dopamine out of the neuron, which is why amphetamine tends to act more strongly.
Methylphenidate vs Amphetamine, side by sideSources and notes
- The sentencefrom sourceMoleculeFinder comparison notesThe pair's answer line.
- The two drawingscomputedPubChem structures, drawn by RDKitThe two drawings side by side.
Properties and sources
Calculated by PubChem
- Molecular formula
- C9H13N
- Molecular weight
- 135.21 g/mol
- XLogP3octanol/water, log units
- 1.8
- Polar surface areatopological
- 26 Ų
- H-bond donors
- 1
- H-bond acceptors
- 1
- Rotatable bonds
- 2
- Complexity
- 84
Measured LD50, HSDB via PubChem
22 mg/kg pure amphetamine, mouse, oral
An LD50 is an animal study measurement, not a dose for a person.
Reported Hazard label (GHS), ECHA, HSDB via PubChem
Danger Flammable pictogram (GHS02), Toxic pictogram (GHS06) and Health hazard pictogram (GHS08); hazard statements H225, H226, H300, H301, H311, H331, H370
Reported Licence
The US Food and Drug Administration licenses Amphetamine for human use (NDA 204326, authorized January 27, 2016), as Adzenys XR-ODT. Drugs@FDA
Groups it belongs to
- Category
- Prescription medicine
- Family
- Stimulants
- Elements
- Nitrogen
- Hazard classes
- Flammable, Acutely toxic, Health hazard, GHS Danger
CC(CC1=CC=CC=C1)NPubChem CID 3007 · Wikidata Q179452 · InChIKey KWTSXDURSIMDCE-UHFFFAOYSA-N · Data refreshed
Questions
- What is Amphetamine?
- The stimulant at the root of the whole class, used for ADHD and narcolepsy and sold as Adderall in a mixed-salt form. A single phenyl ring, a two-carbon chain, an amine.
- How toxic is Amphetamine?
- The reported LD50 of Amphetamine is 22 mg/kg (mouse, oral). An LD50 is an animal study measurement, not a dose for a person. Its GHS hazard label carries the signal word Danger and the hazard pictograms Flammable, Toxic and Health hazard. from sourcefrom source
- What kind of molecule is Amphetamine?
- Amphetamine has the formula C9H13N and a molecular weight of 135.21 g/mol. MoleculeFinder files it under stimulants, in the prescription medicine group. from sourcefrom sourcefrom sourcefrom source
- What else is Amphetamine called?
- Amphetamine is also called α-methylphenethylamine, β-aminopropylbenzene, β-phenylisopropylamine and beta-aminopropylbenzene. from source
- Who licenses Amphetamine as a medicine?
- The US Food and Drug Administration licenses Amphetamine for human use (NDA 204326, authorized January 27, 2016), as Adzenys XR-ODT. from source
Sources and notes
- Calculated valuescomputedPubChemComputed from the structure, so no laboratory conditions apply; complexity is PubChem's own structural score.
- LD50from sourceHSDB via PubChemOther values the sources report: mouse, another route, 16 mg/kg; rat, another route, 39 mg/kg; rat, another route, 125 mg/kg. The page shows the one LD50 the site uses everywhere.
- Hazard labelfrom sourceECHA, HSDB via PubChemThe label combines these classifications.
- ECHAfrom sourceAttributionSource: European Chemicals Agency, echa.europa.eu.
- Licencefrom sourceDrugs@FDARead 2026-10-21.
- Data refreshedfrom sourceMoleculeFinder2026-11-09
Keep exploring
More related molecules
- Levomethamphetamine Both carry an amine group.
- Phenylalanine Both carry an amine group.
- Selegiline Both carry an aromatic ring.
- Phenethylamine Both carry an amine group.
- Benzyl alcohol Both carry an aromatic ring.
- Aspartame Both carry an amine group.
Sources and notes
- Compared side by sidefrom sourceMoleculeFinder comparison notesA molecule we compare it with on its own page.
- The same kind of moleculefrom sourceMoleculeFinder curated groupsA structural neighbour in the same family or type group; the line names the group in its own words.
- Similar in shapecomputedRDKit Morgan/TanimotoNeighbours by structural fingerprint; the sentence names the chemical groups the two share.
- The drawingscomputedPubChem structures, drawn by RDKit