Lisdexamfetamine
Also called L-lysine-d-amphetamine.
A stimulant sold as Vyvanse, used for ADHD and binge eating disorder. It is amphetamine with the amino acid lysine bolted on, inert until the body cuts it off.
Sources and notes
- The introductionfrom sourceMoleculeFinder curated
- Other namesfrom sourcePubChem / Wikidata
- Formula and weightcomputedPubChem
- 2D drawingcomputedPubChem structure, drawn by RDKit
- 3D modelfrom sourcePubChem 3D conformerLoaded after the page has painted, and on a phone only when you ask for it; the 2D drawing shows until it arrives.
Where you encounter it
Dispensed on prescription, not sold on a shelf. Lisdexamfetamine on the product labels we hold.
Medicines
Every product and list we hold
Sources and notes
- The product labels and their strengthsfrom sourceDailyMed (FDA label)Each label lists the molecule as an ingredient, and an active ingredient at the strength shown.
- How it gets therefrom sourceMoleculeFinder curatedEach mark is set by hand on our lists, never inferred; a label's ingredient is added by the maker. A row with no mark data says Not marked.
- The line abovefrom sourceMoleculeFinder curatedFrom the group the molecule belongs to.
Explore its structure
Choose a part to light it up.
A C=O bonded to a nitrogen, the same link that joins amino acids in a protein. It is sturdy, and its nitrogen is not a base the way an amine's is.
From: standard chemistry.
A nitrogen carrying one or two hydrogens. Its spare pair of electrons can pick up a hydrogen ion, so an amine is a base.
From: standard chemistry.
Six carbons in a flat hexagon, sharing their electrons evenly around the ring. It is stable, flat and oily, and it stacks readily against other flat rings.
From: standard chemistry.
Sources and notes
- The drawingcomputedPubChem structure, drawn by RDKitThe page's one shipped drawing, with the chosen part lit in amber under it.
- The partscomputedFound by ruleEach part is found by a chemical pattern, never picked by hand atom by atom; its words say where they come from.
Compare a related molecule
Lisdexamfetamine
Dextroamphetamine
Lisdexamfetamine is dextroamphetamine with the amino acid lysine attached, and it does nothing until the blood cuts the lysine off.
Lisdexamfetamine vs Dextroamphetamine, side by sideSources and notes
- The sentencefrom sourceMoleculeFinder comparison notesThe pair's answer line.
- The two drawingscomputedPubChem structures, drawn by RDKitThe two drawings side by side.
Properties and sources
Calculated by PubChem
- Molecular formula
- C15H25N3O
- Molecular weight
- 263.38 g/mol
- XLogP3octanol/water, log units
- 1.2
- Polar surface areatopological
- 81.1 Ų
- H-bond donors
- 3
- H-bond acceptors
- 3
- Rotatable bonds
- 8
- Complexity
- 252
Reported Hazard label (GHS), HSDB via PubChem
Danger Flammable pictogram (GHS02), Toxic pictogram (GHS06) and Health hazard pictogram (GHS08); hazard statements H225, H301, H311, H331, H370
Reported Licence
The US Food and Drug Administration licenses Lisdexamfetamine for human use (NDA 021977, authorized February 23, 2007), as Vyvanse. Drugs@FDA
Groups it belongs to
- Category
- Prescription medicine
- Family
- Stimulants
- Elements
- Nitrogen
- Hazard classes
- Flammable, Acutely toxic, Health hazard, GHS Danger
C[C@@H](CC1=CC=CC=C1)NC(=O)[C@H](CCCCN)NPubChem CID 11597698 · Wikidata Q6558704 · InChIKey VOBHXZCDAVEXEY-JSGCOSHPSA-N · Data refreshed
Questions
- What is Lisdexamfetamine?
- A stimulant sold as Vyvanse, used for ADHD and binge eating disorder. It is amphetamine with the amino acid lysine bolted on, inert until the body cuts it off.
- How toxic is Lisdexamfetamine?
- Its GHS hazard label carries the signal word Danger and the hazard pictograms Flammable, Toxic and Health hazard. from source
- What kind of molecule is Lisdexamfetamine?
- Lisdexamfetamine has the formula C15H25N3O and a molecular weight of 263.38 g/mol. MoleculeFinder files it under stimulants, in the prescription medicine group. from sourcefrom sourcefrom sourcefrom source
- Who licenses Lisdexamfetamine as a medicine?
- The US Food and Drug Administration licenses Lisdexamfetamine for human use (NDA 021977, authorized February 23, 2007), as Vyvanse. from source
Sources and notes
- Calculated valuescomputedPubChemComputed from the structure, so no laboratory conditions apply; complexity is PubChem's own structural score.
- Hazard labelfrom sourceHSDB via PubChemThe label combines these classifications.
- Licencefrom sourceDrugs@FDARead 2026-10-21.
- Data refreshedfrom sourceMoleculeFinder2026-11-09
Keep exploring
More related molecules
- Lysine Both carry an amine group.
- Levomethamphetamine Both carry an amine group.
- Ornithine Both carry an amine group.
Sources and notes
- Compared side by sidefrom sourceMoleculeFinder comparison notesA molecule we compare it with on its own page.
- The same kind of moleculefrom sourceMoleculeFinder curated groupsA structural neighbour in the same family or type group; the line names the group in its own words.
- Similar in shapecomputedRDKit Morgan/TanimotoNeighbours by structural fingerprint; the sentence names the chemical groups the two share.
- The drawingscomputedPubChem structures, drawn by RDKit