SHEET /m/methyl-salicylate · PubChem CID 4133 · CAS 119-36-8 · REV 2026.07
Methyl salicylate
from sourceC8H8O3 · 152.15 g/mol
Methyl o-hydroxybenzoate · Gaultheria oil · Oil of wintergreen · Betula oil
What is Methyl salicylate?
Oil of wintergreen, the smell of muscle rubs like Bengay and of root beer. It is chemically close to aspirin and absorbs through skin. from source
Fig. 1 · 2D structure RDKit
COC(=O)C1=CC=CC=C1OThe dose makes the poison inferred
A reported rat oral LD50 for Methyl salicylate is 887 mg/kg, the dose lethal to half the animals tested. Scaled by body mass alone:
“The dose makes the poison” is a cross-species estimate shown as neutral science, not a threshold anyone should act on. Real toxicity depends on the person, not body mass alone.
Toxicity & hazards
Toxicity · LD50
887 mg/kg · low toxicity · LD50 rat oral from source
The dose lens above scales this to a body weight.
3 more reported values
- 1,060 mg/kgLD50 · oral · guinea pig
- 2,100 mg/kgLD50 · oral · dog
- 2,800 mg/kgLD50 · oral · rabbit
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