Fluoxetine
Also called Prozac.
The first blockbuster SSRI, sold as Prozac, used for depression, OCD and bulimia. Its three fluorine atoms give it an unusually long stay in the body.
Sources and notes
- The introductionfrom sourceMoleculeFinder curated
- Other namesfrom sourceWikidataIts English label and aliases on Wikidata.
- Formula and weightcomputedPubChem
- 2D drawingcomputedPubChem structure, drawn by RDKit
- 3D modelfrom sourcePubChem 3D conformerLoaded after the page has painted, and on a phone only when you ask for it; the 2D drawing shows until it arrives.
Where you encounter it
Dispensed on prescription, not sold on a shelf. Fluoxetine on the product labels we hold.
Medicines
Every product and list we hold
Sources and notes
- The product labels and their strengthsfrom sourceDailyMed (FDA label)Each label lists the molecule as an ingredient, and an active ingredient at the strength shown.
- How it gets therefrom sourceMoleculeFinder curatedEach mark is set by hand on our lists, never inferred; a label's ingredient is added by the maker. A row with no mark data says Not marked.
- The line abovefrom sourceMoleculeFinder curatedFrom the group the molecule belongs to.
Explore its structure
Choose a part to light it up.
A nitrogen carrying one or two hydrogens. Its spare pair of electrons can pick up a hydrogen ion, so an amine is a base.
From: standard chemistry.
An oxygen bridging two carbons, written C-O-C. It accepts hydrogen bonds but has no hydrogen to give, and it is slow to react.
From: standard chemistry.
Fluorine, chlorine, bromine or iodine bonded to carbon. Each pulls electrons toward itself, and each is larger than the hydrogen the carbon would otherwise carry.
From: standard chemistry.
Sources and notes
- The drawingcomputedPubChem structure, drawn by RDKitThe page's one shipped drawing, with the chosen part lit in amber under it.
- The partscomputedFound by ruleEach part is found by a chemical pattern, never picked by hand atom by atom; its words say where they come from.
Compare a related molecule
Sertraline
Fluoxetine
Sertraline and fluoxetine are both SSRIs, but fluoxetine and its active metabolite linger for a week or more while sertraline clears in a day or two.
Sertraline vs Fluoxetine, side by sideSources and notes
- The sentencefrom sourceMoleculeFinder comparison notesThe pair's answer line.
- The two drawingscomputedPubChem structures, drawn by RDKitThe two drawings side by side.
Properties and sources
Calculated by PubChem
- Molecular formula
- C17H18F3NO
- Molecular weight
- 309.33 g/mol
- XLogP3octanol/water, log units
- 4
- Polar surface areatopological
- 21.3 Ų
- H-bond donors
- 1
- H-bond acceptors
- 5
- Rotatable bonds
- 6
- Complexity
- 308
Reported Hazard label (GHS), ECHA via PubChem
Danger Corrosive pictogram (GHS05), Toxic pictogram (GHS06), Health hazard pictogram (GHS08) and Environmental pictogram (GHS09); hazard statements H302, H315, H318, H330, H336, H373, H410
Reported Licence
The US Food and Drug Administration licenses Fluoxetine for human use (ANDA 075049, authorized August 2, 2001). Drugs@FDA
Groups it belongs to
- Category
- Prescription medicine
- Family
- SSRIs
- Chemical groups
- Amines, Aromatics, Ethers, Halogenated
- Hazard classes
- Corrosive, Acutely toxic, Health hazard, Environmental hazard, GHS Danger
CNCCC(C1=CC=CC=C1)OC2=CC=C(C=C2)C(F)(F)FPubChem CID 3386 · Wikidata Q422244 · InChIKey RTHCYVBBDHJXIQ-UHFFFAOYSA-N · Data refreshed
Questions
- What is Fluoxetine?
- The first blockbuster SSRI, sold as Prozac, used for depression, OCD and bulimia. Its three fluorine atoms give it an unusually long stay in the body.
- How toxic is Fluoxetine?
- Its GHS hazard label carries the signal word Danger and the hazard pictograms Corrosive, Toxic, Health hazard and Environmental. from source
- What kind of molecule is Fluoxetine?
- Fluoxetine has the formula C17H18F3NO and a molecular weight of 309.33 g/mol. MoleculeFinder files it under SSRIs, in the prescription medicine group. from sourcefrom sourcefrom sourcefrom source
- What else is Fluoxetine called?
- Fluoxetine is also called Prozac. from source
- Who licenses Fluoxetine as a medicine?
- The US Food and Drug Administration licenses Fluoxetine for human use (ANDA 075049, authorized August 2, 2001). from source
Sources and notes
- Calculated valuescomputedPubChemComputed from the structure, so no laboratory conditions apply; complexity is PubChem's own structural score.
- Hazard labelfrom sourceECHA via PubChemThe label combines these classifications.
- ECHAfrom sourceAttributionSource: European Chemicals Agency, echa.europa.eu.
- Licencefrom sourceDrugs@FDARead 2026-10-21.
- Data refreshedfrom sourceMoleculeFinder2026-11-09
Keep exploring
Sources and notes
- Compared side by sidefrom sourceMoleculeFinder comparison notesA molecule we compare it with on its own page.
- Similar in shapecomputedRDKit Morgan/TanimotoNeighbours by structural fingerprint; the sentence names the chemical groups the two share.
- The drawingscomputedPubChem structures, drawn by RDKit