SHEET /m/doxepin · PubChem CID 3158 · CAS 1668-19-5 · REV 2026.07
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Doxepin
from sourceC19H21NO · 279.4 g/mol
Sinepin · Sinquan
What is Doxepin?
A tricyclic antidepressant, now more often prescribed at low strength for insomnia and for itching. Doxepin (C19H21NO, 279 g/mol) is a tricyclic antidepressant dispensed on prescription. from source
CategoryPrescription medicine
Fig. 1 · 2D structure RDKit
SMILES
CN(C)CCC=C1C2=CC=CC=C2COC3=CC=CC=C31Where you'll find it
Dispensed on prescription, not sold on a shelf. See the rest of the prescription medicine group.
Relative acute toxicity from source
Animal study data · LD50
- Reported LD50
- 147 mg/kg · moderately toxic
- Species
- rat
- Route
- oral
An LD50 describes acute toxicity under experimental conditions and is not a safe or dangerous dose for a person.
Toxicity & hazards
Toxicity · LD50
147 mg/kg · moderately toxic · LD50 rat oral from source
4 more reported values
- 135 mg/kgLD50 · oral · mouse
- 16 mg/kgLD50 · iv · rat
- 26 mg/kgLD50 · iv · mouse
- 182 mg/kgLD50 · other · rat
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