SHEET /m/cyclobenzaprine · PubChem CID 2895 · CAS 303-53-7 · REV 2026.07
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Cyclobenzaprine
from sourceC20H21N · 275.4 g/mol
Fexmid · Lisseril · Proeptatriene · Proheptatrien
What is Cyclobenzaprine?
A muscle relaxant sold as Flexeril, used short term for muscle spasm. Its skeleton is a tricyclic antidepressant's, one double bond apart from amitriptyline. from source
CategoryPrescription medicine
Chemical familyAromatics
Fig. 1 · 2D structure RDKit
SMILES
CN(C)CCC=C1C2=CC=CC=C2C=CC3=CC=CC=C31Where you'll find it
Dispensed on prescription, not sold on a shelf. See the rest of the prescription medicine group.
Relative acute toxicity from source
Animal study data · LD50
- Reported LD50
- 425 mg/kg · low toxicity
- Species
- rat
- Route
- oral
An LD50 describes acute toxicity under experimental conditions and is not a safe or dangerous dose for a person.
Toxicity & hazards
Toxicity · LD50
425 mg/kg · low toxicity · LD50 rat oral from source
4 more reported values
- 250 mg/kgLD50 · oral · mouse
- 338 mg/kgLD50 · oral · mouse
- 36 mg/kgLD50 · iv · mouse
- 90 mg/kgLD50 · other · mouse
DangerToxicIrritantH301, H312, H332from source
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