What is the active ingredient in Prilosec OTC and in Nexium 24HR?

Prilosec OTC's label lists omeprazole 20 mg (equivalent to 20.6 mg omeprazole magnesium), acid reducer as its active ingredient. Nexium 24HR's label lists esomeprazole 20 mg in each tablet, acid reducer as its active ingredient.

Which ingredients do Prilosec OTC and Nexium 24HR share?

Both labels list starch, Allura Red AC, magnesium stearate, cellulose, polysorbate 80, sucrose, triethyl citrate, methacrylic acid - methyl methacrylate copolymer (1:1), glyceryl monostearate, hydroxypropyl cellulose (1600000 wamw), mica, sodium stearyl fumarate, talc and titanium dioxide.

What's in Prilosec OTC vs Nexium 24HR?

from source

Prilosec OTC's active ingredient is omeprazole and Nexium 24HR's is esomeprazole; the two labels share most of their inactive ingredients.

This page compares the two labels' ingredient lists as DailyMed carries them, not what either product does. Prilosec OTC: the label on DailyMed from The Procter & Gamble Manufacturing Company lists 20 ingredients, 8 of them MoleculeFinder molecules. What's in Prilosec OTC. Nexium 24HR: the label on DailyMed from Haleon US Holdings LLC lists 21 ingredients, 7 of them MoleculeFinder molecules. What's in Nexium 24HR.

Active ingredients

Prilosec OTC

OmeprazoleC17H19N3O3S
Active ingredient, 20 mg (equivalent to 20.6 mg omeprazole magnesium). Purpose on the label: Acid reducer (on the label as omeprazole magnesium) from source

Nexium 24HR

EsomeprazoleC17H19N3O3S
Active ingredient, 20 mg in each tablet. Purpose on the label: Acid reducer (on the label as esomeprazole magnesium trihydrate) from source

Inactive ingredients both list 14

Starch
Inactive ingredient on both labels (on Prilosec OTC's label as starch, rice; on Nexium 24HR's label as starch, corn) from source
Allura Red ACC18H14N2Na2O8S2
Inactive ingredient on both labels (on Prilosec OTC's label as FD&C red No. 40) from source
Magnesium stearateC36H70MgO4
Inactive ingredient on both labels from source
Cellulose
Inactive ingredient on both labels (on Prilosec OTC's label as cellulose, microcrystalline; on Nexium 24HR's label as microcrystalline cellulose) from source
Polysorbate 80C32H60O10
Inactive ingredient on both labels from source
SucroseC12H22O11
Inactive ingredient on both labels from source

triethyl citrate
methacrylic acid - methyl methacrylate copolymer (1:1)
glyceryl monostearate
hydroxypropyl cellulose (1600000 wamw)
mica
sodium stearyl fumarate
talc
titanium dioxide

Only on Prilosec OTC's label 5

SaccharinC7H5NO3S
Inactive ingredient (on the label as saccharin sodium) from source

povidone k60
FD&C blue No. 2 aluminum lake
hypromelloses
polyethylene glycol 6000

Only on Nexium 24HR's label 6

crospovidone (120 .mu.m)
D&C red No. 27
FD&C blue No. 2
hypromellose, unspecified
paraffin
polyethylene glycol, unspecified

Common questions

What is the difference between Prilosec OTC and Nexium 24HR?: Prilosec OTC's active ingredient is omeprazole and Nexium 24HR's is esomeprazole; the two labels share most of their inactive ingredients.
What is the active ingredient in Prilosec OTC and in Nexium 24HR?: Prilosec OTC's label lists omeprazole 20 mg (equivalent to 20.6 mg omeprazole magnesium), acid reducer as its active ingredient. Nexium 24HR's label lists esomeprazole 20 mg in each tablet, acid reducer as its active ingredient.
Which ingredients do Prilosec OTC and Nexium 24HR share?: Both labels list starch, Allura Red AC, magnesium stearate, cellulose, polysorbate 80, sucrose, triethyl citrate, methacrylic acid - methyl methacrylate copolymer (1:1), glyceryl monostearate, hydroxypropyl cellulose (1600000 wamw), mica, sodium stearyl fumarate, talc and titanium dioxide.

Product names are used only to name the products; MoleculeFinder makes no claim about either beyond its ingredient list. Unlinked names are the labels' own, for ingredients that are not yet MoleculeFinder molecules. Every product