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SHEET /vs/glucose-vs-glycogen · COMPARISON

Glucose vs Glycogen: what is the difference?

GlucoseC6H12O6 GlycogenC24H42O21

How they differ

from source

Glycogen is not a different sugar, it is thousands of glucose units branched together, which is why its listed formula and weight represent a fragment rather than a fixed molecule. The body keeps glucose in the blood within a narrow range and stores the rest as glycogen in the liver and muscle, unpacking it when the level drops. Branching is the point: a branched chain has many free ends, so many enzymes can strip glucose off at once and release it quickly. Muscle glycogen is only available to that muscle, while liver glycogen is released into the blood for the whole body. Carb-loading before an endurance event is about filling those stores rather than about eating any particular sugar.

Side by side

 GlucoseGlycogen
FormulaC6H12O6C24H42O21
Molecular weight180.16 g/mol666.6 g/mol
FamilySugarsSugars
Everyday groupSweetenerBody
Functional groupsAlcohols, EthersAlcohols, Ethers
Oral LD50A single acute animal measure. It ranks nothing about human safety.25,800 mg/kg (oral, rat)not recorded
Sweetness0.75x sugarnot recorded
Found inFruit, Honey, Table sugarnot recorded
CAS numbernot recorded9005-79-2
PubChem CID5793439177

Structural similarity 0.50 of 1, computed as a Morgan fingerprint Tanimoto coefficient. It measures shape, not effect.

Common questions

What is the difference between Glucose and Glycogen?
Glycogen is not a different sugar, it is thousands of glucose units branched together, which is why its listed formula and weight represent a fragment rather than a fixed molecule. The body keeps glucose in the blood within a narrow range and stores the rest as glycogen in the liver and muscle, unpacking it when the level drops. Branching is the point: a branched chain has many free ends, so many enzymes can strip glucose off at once and release it quickly.
Is Glucose bigger than Glycogen?
Glycogen is the heavier molecule, 666.6 g/mol against 180.16 g/mol for Glucose. Glucose is C6H12O6 and Glycogen is C24H42O21.

Read the full records: Glucose and Glycogen.