SHEET /m/tretinoin · PubChem CID 444795 · CAS 302-79-4 · REV 2026.07
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Tretinoin
from sourceC20H28O2 · 300.4 g/mol
beta-Retinoate · trans-Retinoate · Retinoate · trans-Retinoic acid
What is Tretinoin?
All-trans retinoic acid, the acid form of vitamin A. It is the prescription retinoid for acne and photoaging, and a treatment for one leukaemia. from source
CategoryPrescription medicine
Chemical familyCarboxylic Acids
Fig. 1 · 2D structure RDKit
SMILES
CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C/C(=O)O)/C)/CWhere you'll find it
Curated by MoleculeFinder from source
Relative acute toxicity from source
Animal study data · LD50
- Reported LD50
- 1,960 mg/kg · low toxicity
- Species
- rat
- Route
- oral
An LD50 describes acute toxicity under experimental conditions and is not a safe or dangerous dose for a person.
Toxicity & hazards
Toxicity · LD50
1,960 mg/kg · low toxicity · LD50 rat oral from source
3 more reported values
- 53 mg/kgLD50 · other · rat
- 78 mg/kgLD50 · iv · rat
- 96 mg/kgLD50 · other · rat
DangerIrritantHealth hazardEnvironmentalH302, H315, H319, H335, H360, H400, H401, H410, H411from source
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Where Tretinoin leads
Relatedcomputed
Isotretinoin100% similarBoth carry a carboxylic acid group.β-Carotene80% similarRetinal77% similarNo functional group in common: Retinal carries an aldehyde group, while Tretinoin carries a carboxylic acid group.11-cis retinal77% similarNo functional group in common: 11-cis retinal carries an aldehyde group, while Tretinoin carries a carboxylic acid group.Retinol70% similarNo functional group in common: Retinol carries an alcohol group, while Tretinoin carries a carboxylic acid group.β-Ionone62% similarNo functional group in common: β-Ionone carries a ketone group, while Tretinoin carries a carboxylic acid group.