Tizanidine
Also called Relentus.
A muscle relaxant for spasticity that works as an alpha-2 agonist, the same mechanism as clonidine. Tizanidine (C9H8ClN5S, 254 g/mol) is a muscle relaxant dispensed on prescription.
Sources and notes
- The introductionfrom sourceMoleculeFinder curated
- Other namesfrom sourceWikidataIts English label and aliases on Wikidata.
- Formula and weightcomputedPubChem
- 2D drawingcomputedPubChem structure, drawn by RDKit
- 3D modelfrom sourcePubChem 3D conformerLoaded after the page has painted, and on a phone only when you ask for it; the 2D drawing shows until it arrives.
Where you encounter it
Dispensed on prescription, not sold on a shelf. Tizanidine on the product labels we hold.
Medicines
Every product and list we hold
Sources and notes
- The product labels and their strengthsfrom sourceDailyMed (FDA label)Each label lists the molecule as an ingredient, and an active ingredient at the strength shown.
- How it gets therefrom sourceMoleculeFinder curatedEach mark is set by hand on our lists, never inferred; a label's ingredient is added by the maker. A row with no mark data says Not marked.
- The line abovefrom sourceMoleculeFinder curatedFrom the group the molecule belongs to.
Explore its structure
Choose a part to light it up.
A carbon bonded to three nitrogens, one of them by a double bond, the same group the amino acid arginine carries. Its N-H groups form hydrogen bonds readily.
From: standard chemistry.
Fluorine, chlorine, bromine or iodine bonded to carbon. Each pulls electrons toward itself, and each is larger than the hydrogen the carbon would otherwise carry.
From: standard chemistry.
Rings joined where they share atoms, or a single ring standing alone. Atoms in a ring are held in place, so this part keeps its shape while chains around it can bend.
From: standard chemistry.
Sources and notes
- The drawingcomputedPubChem structure, drawn by RDKitThe page's one shipped drawing, with the chosen part lit in amber under it.
- The partscomputedFound by ruleEach part is found by a chemical pattern, never picked by hand atom by atom; its words say where they come from.
Properties and sources
Calculated by PubChem
- Molecular formula
- C9H8ClN5S
- Molecular weight
- 253.71 g/mol
- XLogP3octanol/water, log units
- 1.1
- Polar surface areatopological
- 90.4 Ų
- H-bond donors
- 2
- H-bond acceptors
- 4
- Rotatable bonds
- 2
- Complexity
- 300
Reported Hazard label (GHS), ECHA via PubChem
Warning Irritant pictogram (GHS07) and Health hazard pictogram (GHS08); hazard statements H302, H332, H361
Reported Licence
The US Food and Drug Administration licenses Tizanidine for human use (NDA 020397, authorized November 27, 1996). Drugs@FDA
Groups it belongs to
- Category
- Prescription medicine
- Family
- Muscle relaxants
- Chemical groups
- Amines, Aromatics, Halogenated
- Hazard classes
- Irritant, Health hazard, GHS Warning
C1CN=C(N1)NC2=C(C=CC3=NSN=C32)ClPubChem CID 5487 · Wikidata Q423538 · InChIKey XFYDIVBRZNQMJC-UHFFFAOYSA-N · Data refreshed
Questions
- What is Tizanidine?
- A muscle relaxant for spasticity that works as an alpha-2 agonist, the same mechanism as clonidine. Tizanidine (C9H8ClN5S, 254 g/mol) is a muscle relaxant dispensed on prescription.
- How toxic is Tizanidine?
- Its GHS hazard label carries the signal word Warning and the hazard pictograms Irritant and Health hazard. from source
- What kind of molecule is Tizanidine?
- Tizanidine has the formula C9H8ClN5S and a molecular weight of 253.71 g/mol. MoleculeFinder files it under muscle relaxants, in the prescription medicine group. from sourcefrom sourcefrom sourcefrom source
- What else is Tizanidine called?
- Tizanidine is also called Relentus. from source
- Who licenses Tizanidine as a medicine?
- The US Food and Drug Administration licenses Tizanidine for human use (NDA 020397, authorized November 27, 1996). from source
Sources and notes
- Calculated valuescomputedPubChemComputed from the structure, so no laboratory conditions apply; complexity is PubChem's own structural score.
- Hazard labelfrom sourceECHA via PubChemThe label combines these classifications.
- ECHAfrom sourceAttributionSource: European Chemicals Agency, echa.europa.eu.
- Licencefrom sourceDrugs@FDARead 2026-10-21.
- Data refreshedfrom sourceMoleculeFinder2026-11-09
Keep exploring
Sources and notes
- Similar in shapecomputedRDKit Morgan/TanimotoNeighbours by structural fingerprint; the sentence names the chemical groups the two share.
- The drawingscomputedPubChem structures, drawn by RDKit