SHEET /m/tacrolimus · PubChem CID 445643 · CAS 104987-11-3 · REV 2026.07
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Tacrolimus
from sourceC44H69NO12 · 804 g/mol
fujimycin · Advagraf · Modigraf · Prograf
What is Tacrolimus?
An immunosuppressant from a Japanese soil bacterium, used to stop organ rejection after transplant and as an eczema ointment. from source
CategoryPrescription medicine
Fig. 1 · 2D structure RDKit
SMILES
C[C@@H]1C[C@@H]([C@@H]2[C@H](C[C@H]([C@@](O2)(C(…176 charactersWhere you'll find it
Dispensed on prescription, not sold on a shelf. See the rest of the prescription medicine group.
Relative acute toxicity from source
Animal study data · LD50
- Reported LD50
- 134 mg/kg · moderately toxic
- Species
- rat
- Route
- oral
An LD50 describes acute toxicity under experimental conditions and is not a safe or dangerous dose for a person.
Toxicity & hazards
Toxicity · LD50
134 mg/kg · moderately toxic · LD50 rat oral from source
1 more reported value
- 23.6 mg/kgLD50 · iv · rat
DangerToxicHealth hazardH301, H361, H372from source