Sirolimus

from source

C51H79NO13 · 914.2 g/mol

rapamycin · RAPA · rapalimus · Rapammune

What is Sirolimus?

An immunosuppressant sold as Rapamune, used after kidney transplants. It was found in a soil bacterium from Easter Island, Rapa Nui, hence its other name, rapamycin. from source

CategoryPrescription medicine

Chemical familyAlcohols Ketones Esters Amides Ethers

LeaderboardsBiggest Deadliest

Fig. 1 · 2D structure RDKit

SMILESC[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@…193 characters

Where you'll find it

Dispensed on prescription, not sold on a shelf. See the rest of the prescription medicine group.

Relative acute toxicity from source

Animal study data · LD50

Reported LD50: 800 mg/kg · low toxicity
Species: rat
Route: oral

An LD50 describes acute toxicity under experimental conditions and is not a safe or dangerous dose for a person.

Toxicity & hazards

Toxicity · LD50

800 mg/kg · low toxicity · LD50 rat oral from source

3 more reported values

800 mg/kgLD50 · oral · mouse
2,500 mg/kgLD50 · oral · mouse
600 mg/kgLD50 · other · mouse

DangerHealth hazardH341, H351, H361, H372from source

Keep roaming

Where Sirolimus leads

Sources & methodology

PubChem CID: 5284616
Wikidata: Q32089
Structure: PubChem → RDKit
LD50: PubChem
Similar molecules: MoleculeFinder fingerprint similarity
Data refreshed: October 19, 2026

How MoleculeFinder sources and labels its data