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SHEET /m/ropinirole · PubChem CID 5095 · CAS 91374-21-9 · REV 2026.07

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Ropinirole

from source

C16H24N2O · 260.37 g/mol

Adartrel · Narapin · Ropitor

What is Ropinirole?

A dopamine agonist sold as Requip, used for Parkinson's disease and restless legs syndrome. It mimics dopamine at the D2 and D3 receptors. from source

Chemical familyAromaticsAmides
LeaderboardsBiggestDeadliest

Fig. 1 · 2D structure RDKit

SMILESCCCN(CCC)CCC1=C2CC(=O)NC2=CC=C1

Where you'll find it

Dispensed on prescription, not sold on a shelf. See the rest of the prescription medicine group.

Relative acute toxicity from source

Animal study data · LD50

Reported LD50
862 mg/kg · low toxicity
Species
rat
Route
oral

An LD50 describes acute toxicity under experimental conditions and is not a safe or dangerous dose for a person.

Toxicity & hazards

Toxicity · LD50

862 mg/kg · low toxicity · LD50 rat oral from source

3 more reported values
  • 657 mg/kgLD50 · oral · mouse
  • 46 mg/kgLD50 · iv · mouse
  • 66 mg/kgLD50 · iv · rat
WarningIrritantEnvironmentalH302, H400, H410, H412from source

Compare with

Sources & methodology

PubChem CID
5095
Wikidata
Q420590
Structure
PubChem → RDKit
LD50
PubChem
Data refreshed

How MoleculeFinder sources and labels its data