SHEET /m/nifedipine · PubChem CID 4485 · CAS 21829-25-4 · REV 2026.07
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Nifedipine
from sourceC17H18N2O6 · 346.3 g/mol
Adipine · Nifecor · Adapine · Nifecard
What is Nifedipine?
A calcium channel blocker sold as Adalat and Procardia, used for high blood pressure and angina. It widens blood vessels by keeping calcium out of their muscle. from source
CategoryPrescription medicine
Fig. 1 · 2D structure RDKit
SMILES
CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC=CC=C2[N+](=O)[O-])C(=O)OCWhere you'll find it
Dispensed on prescription, not sold on a shelf. See the rest of the prescription medicine group.
Relative acute toxicity from source
Animal study data · LD50
- Reported LD50
- 1,022 mg/kg · low toxicity
- Species
- rat
- Route
- oral
An LD50 describes acute toxicity under experimental conditions and is not a safe or dangerous dose for a person.
Toxicity & hazards
Toxicity · LD50
1,022 mg/kg · low toxicity · LD50 rat oral from source
4 more reported values
- 310 mg/kgLD50 · oral · mouse
- 504 mg/kgLD50 · oral · rabbit
- 185 mg/kgLD50 · other · mouse
- 230 mg/kgLD50 · other · rat
WarningIrritantHealth hazardH302, H361from source
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Where Nifedipine leads
Relatedcomputed