Hydroxyzine

from source

C21H27ClN2O2 · 374.9 g/mol

Ataraxoid · Atarazoid · Hychotine · Hydroxizinum

What is Hydroxyzine?

An older antihistamine used both for itching and, because it is sedating, for anxiety and sleep. Cetirizine is what the body turns it into. from source

CategoryPrescription medicine

Chemical familyAlcohols Aromatics Ethers Halogenated

LeaderboardsBiggest Deadliest

Fig. 1 · 2D structure RDKit

SMILESC1CN(CCN1CCOCCO)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl

Where you'll find it

Dispensed on prescription, not sold on a shelf. See the rest of the prescription medicine group.

Relative acute toxicity from source

Animal study data · LD50

Reported LD50: 840 mg/kg · low toxicity
Species: rat
Route: oral

An LD50 describes acute toxicity under experimental conditions and is not a safe or dangerous dose for a person.

Toxicity & hazards

Toxicity · LD50

840 mg/kg · low toxicity · LD50 rat oral from source

3 more reported values

480 mg/kgLD50 · oral · mouse
45 mg/kgLD50 · iv · rat
160 mg/kgLD50 · other · rat

DangerIrritantHealth hazardH302, H334, H336, H360, H372from source

Keep roaming

Where Hydroxyzine leads

Compare with

Hydroxyzine vs Diphenhydramine

Sources & methodology

PubChem CID: 3658
Wikidata: Q421937
Structure: PubChem → RDKit
LD50: PubChem
Similar molecules: MoleculeFinder fingerprint similarity
Data refreshed: September 13, 2026

How MoleculeFinder sources and labels its data