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SHEET /m/hydrochlorothiazide · PubChem CID 3639 · CAS 58-93-5 · REV 2026.07

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Hydrochlorothiazide

from source

C7H8ClN3O4S2 · 297.7 g/mol

Chlorosulthiadil · Esidrix · HCTZ · Hidrotiazida

What is Hydrochlorothiazide?

A thiazide diuretic, one of the oldest and most prescribed blood-pressure medicines, usually combined with something else in one tablet. from source

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Fig. 1 · 2D structure RDKit

SMILESC1NC2=CC(=C(C=C2S(=O)(=O)N1)S(=O)(=O)N)Cl

Where you'll find it

Dispensed on prescription, not sold on a shelf. See the rest of the prescription medicine group.

Toxicity & hazards

Toxicity · LD50

250 mg/kg · moderately toxic · LD50 dog iv from source

3 more reported values
  • 461 mg/kgLD50 · iv · rabbit
  • 578 mg/kgLD50 · other · mouse
  • 1,470 mg/kgLD50 · other · mouse
DangerIrritantHealth hazardH302, H317, H334, H372from source

Compare with

Sources & methodology

PubChem CID
3639
Wikidata
Q423930
Structure
PubChem → RDKit
LD50
PubChem
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