Fentanyl

from source

C22H28N2O · 336.5 g/mol

Duragesic · Durogesic · Fentanest · Matrifen

What is Fentanyl?

A synthetic opioid painkiller used in surgery and in patches such as Duragesic. It is far more potent by weight than morphine, which is why it dominates overdose statistics. from source

CategoryPrescription medicine

Chemical familyAromatics Amides

LeaderboardsBiggest Deadliest

Fig. 1 · 2D structure RDKit

SMILESCCC(=O)N(C1CCN(CC1)CCC2=CC=CC=C2)C3=CC=CC=C3

Where you'll find it

Dispensed on prescription, not sold on a shelf. See the rest of the prescription medicine group.

Relative acute toxicity from source

Animal study data · LD50

Reported LD50: 18 mg/kg · highly toxic
Species: rat
Route: oral

An LD50 describes acute toxicity under experimental conditions and is not a safe or dangerous dose for a person.

Toxicity & hazards

Toxicity · LD50

18 mg/kg · highly toxic · LD50 rat oral from source

4 more reported values

1.5 mg/kgLD50 · other · rat
2.91 mg/kgLD50 · iv · rat
11.2 mg/kgLD50 · iv · mouse
62 mg/kgLD50 · other · mouse

DangerToxicIrritantHealth hazardH300, H310, H317, H330, H334, H361, H362, H413from source

Keep roaming

Where Fentanyl leads

Compare with

Fentanyl vs Morphine

Sources & methodology

PubChem CID: 3345
Wikidata: Q407541
Structure: PubChem → RDKit
LD50: PubChem
Similar molecules: MoleculeFinder fingerprint similarity
Data refreshed: September 13, 2026

How MoleculeFinder sources and labels its data