moleculefinder

Diclofenac

C14H11Cl2NO2296.1 g/mol Calculated

Also called Allvoran and Zorvolex.

A non-steroidal anti-inflammatory best known over the counter as the Voltaren gel rubbed onto an aching joint.

Sources and notes
  • The introductionfrom sourceMoleculeFinder curated
  • Other namesfrom sourcePubChem / Wikidata
  • Formula and weightcomputedPubChem
  • 2D drawingcomputedPubChem structure, drawn by RDKit
  • 3D modelfrom sourcePubChem 3D conformerLoaded after the page has painted, and on a phone only when you ask for it; the 2D drawing shows until it arrives.

Where you encounter it

Sold over the counter, without a prescription. Diclofenac on the product labels we hold.

Medicines

SalonpasAdded by the makerActive ingredient, 1% (equivalent to 0.93% diclofenac)
Voltaren Arthritis PainAdded by the makerActive ingredient, 1% (equivalent to 0.93% diclofenac)

Every product and list we hold

Sources and notes
  • The product labels and their strengthsfrom sourceDailyMed (FDA label)Each label lists the molecule as an ingredient, and an active ingredient at the strength shown.
  • How it gets therefrom sourceMoleculeFinder curatedEach mark is set by hand on our lists, never inferred; a label's ingredient is added by the maker. A row with no mark data says Not marked.
  • The line abovefrom sourceMoleculeFinder curatedFrom the group the molecule belongs to.

Explore its structure

Choose a part to light it up.

A carbon carrying both a C=O and an O-H, written COOH. In water it gives up that hydrogen, which is what makes the molecule an acid.

From: standard chemistry.

Sources and notes
  • The drawingcomputedPubChem structure, drawn by RDKitThe page's one shipped drawing, with the chosen part lit in amber under it.
  • The partscomputedFound by ruleEach part is found by a chemical pattern, never picked by hand atom by atom; its words say where they come from.

Properties and sources

Calculated by PubChem

Molecular formula
C14H11Cl2NO2
Molecular weight
296.1 g/mol
XLogP3octanol/water, log units
4.4
Polar surface areatopological
49.3 Ų
H-bond donors
2
H-bond acceptors
3
Rotatable bonds
4
Complexity
304

Measured LD50, HSDB via PubChem

500 mg/kg pure diclofenac, dog, oral

An LD50 is an animal study measurement, not a dose for a person.

Reported Hazard label (GHS), ECHA via PubChem

Danger Toxic pictogram (GHS06), Irritant pictogram (GHS07), Health hazard pictogram (GHS08) and Environmental pictogram (GHS09); hazard statements H301, H302, H361, H372, H411

Reported Licence

The US Food and Drug Administration licenses Diclofenac for human use (NDA 022122, authorized October 17, 2007), as Voltaren Arthritis Pain. Drugs@FDA

Groups it belongs to

Category
OTC medicine
Family
NSAIDs
Use
Pain and fever
Chemical groups
Carboxylic Acids, Amines, Aromatics, Halogenated
Elements
Chlorine, Nitrogen
Hazard classes
Acutely toxic, Irritant, Health hazard, Environmental hazard, GHS Danger
SMILESC1=CC=C(C(=C1)CC(=O)O)NC2=C(C=CC=C2Cl)Cl

PubChem CID 3033 · Wikidata Q244408 · InChIKey DCOPUUMXTXDBNB-UHFFFAOYSA-N · Data refreshed

How MoleculeFinder sources and labels its data

Questions
What is Diclofenac?
A non-steroidal anti-inflammatory best known over the counter as the Voltaren gel rubbed onto an aching joint.
How toxic is Diclofenac?
The reported LD50 of Diclofenac is 500 mg/kg (dog, oral). An LD50 is an animal study measurement, not a dose for a person. Its GHS hazard label carries the signal word Danger and the hazard pictograms Toxic, Irritant, Health hazard and Environmental. from sourcefrom source
What kind of molecule is Diclofenac?
Diclofenac has the formula C14H11Cl2NO2 and a molecular weight of 296.1 g/mol. MoleculeFinder files it under NSAIDs, in the OTC medicine group. from sourcefrom sourcefrom sourcefrom source
Who licenses Diclofenac as a medicine?
The US Food and Drug Administration licenses Diclofenac for human use (NDA 022122, authorized October 17, 2007), as Voltaren Arthritis Pain. from source
Sources and notes
  • Calculated valuescomputedPubChemComputed from the structure, so no laboratory conditions apply; complexity is PubChem's own structural score.
  • LD50from sourceHSDB via PubChemOther values the sources report: monkey, oral, 3,200 mg/kg. The page shows the one LD50 the site uses everywhere.
  • Hazard labelfrom sourceECHA via PubChemThe label combines these classifications.
  • ECHAfrom sourceAttributionSource: European Chemicals Agency, echa.europa.eu.
  • Licencefrom sourceDrugs@FDARead 2026-10-21.
  • Data refreshedfrom sourceMoleculeFinder2026-11-09

Keep exploring

Both carry a carboxylic acid group.Phenylacetic acidC8H8O2
Sources and notes
  • Similar in shapecomputedRDKit Morgan/TanimotoNeighbours by structural fingerprint; the sentence names the chemical groups the two share.
  • The drawingscomputedPubChem structures, drawn by RDKit