SHEET /m/diacetyl · PubChem CID 650 · CAS 431-03-8 · REV 2026.07
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Diacetyl from source
C4H6O2 · 86.09 g/mol
2,3-butanedione · biacetyl · Butane-2,3-dione · dimethylglyoxal
chemical compound
CategoryFood & flavor
Chemical familyKetones
Fig. 1 · 2D structure RDKit
CC(=O)C(=O)C
Where you'll find it
Not yet mapped to everyday foods or products.
The dose makes the poison inferred
A reported mouse oral LD50 for Diacetyl is 250 mg/kg, the dose lethal to half the animals tested. Scaled by body mass alone:
17.5 g
a median lethal dose scaled to 154 lb (17,500 mg)
“The dose makes the poison” is a cross-species estimate shown as neutral science, not a threshold anyone should act on. Real toxicity depends on the person, not body mass alone.
Toxicity & hazards
Toxicity · LD50
250 mg/kg · moderately toxic · LD50 mouse oral from source
The dose lens above scales this to a body weight.
1 more reported value
- 1,580 mg/kgLD50 · oral · rat
DangerFlammableCorrosiveToxicIrritantHealth hazardH225, H302, H315, H317, H318, H331, H332, H335, H351, H370, H372, H373from source
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