Bupropion

from source

C13H18ClNO · 239.74 g/mol

amfebutamone · Amfebutamon · Amfebutamona · amfebutamonum

What is Bupropion?

An antidepressant, sold as Wellbutrin and Zyban, also used to help people stop smoking. Chemically it is a substituted cathinone rather than an SSRI. from source

CategoryPrescription medicine

Chemical familyAmines Aromatics Ketones Halogenated

LeaderboardsBiggest Deadliest

Fig. 1 · 2D structure RDKit

SMILESCC(C(=O)C1=CC(=CC=C1)Cl)NC(C)(C)C

Where you'll find it

Dispensed on prescription, not sold on a shelf. See the rest of the prescription medicine group.

Relative acute toxicity from source

Animal study data · LD50

Reported LD50: 600 mg/kg · low toxicity
Species: rat
Route: oral

An LD50 describes acute toxicity under experimental conditions and is not a safe or dangerous dose for a person.

Toxicity & hazards

Toxicity · LD50

600 mg/kg · low toxicity · LD50 rat oral from source

3 more reported values

575 mg/kgLD50 · oral · mouse
210 mg/kgLD50 · other · rat
230 mg/kgLD50 · other · mouse

WarningIrritantH302from source

Compare with

Bupropion vs Sertraline

Sources & methodology

PubChem CID: 444
Wikidata: Q834280
Structure: PubChem → RDKit
LD50: PubChem
Data refreshed: September 13, 2026

How MoleculeFinder sources and labels its data