Testosterone enanthate vs Testosterone cypionate: what is the difference?

How they differ

Both are testosterone with a fatty tail attached at the same oxygen, and the tail is the only difference: a straight seven-carbon enanthate chain against a cyclopentylpropionate group. That makes cypionate one carbon heavier, C27H40O3 at 412.6 against C26H40O3 at 400.6. The tail holds the molecule in an oily injection depot, and the body clips it off to release plain testosterone, so the two behave almost identically once inside. Cypionate is the common injectable in the United States, sold as Depo-Testosterone, while enanthate is more widely used elsewhere and in the Xyosted autoinjector.

Side by side

Structural similarity 0.74 of 1, computed as a Morgan fingerprint Tanimoto coefficient. It measures shape, not effect.

Common questions

What is the difference between Testosterone enanthate and Testosterone cypionate?

Both are testosterone with a fatty tail attached at the same oxygen, and the tail is the only difference: a straight seven-carbon enanthate chain against a cyclopentylpropionate group. That makes cypionate one carbon heavier, C27H40O3 at 412.6 against C26H40O3 at 400.6. The tail holds the molecule in an oily injection depot, and the body clips it off to release plain testosterone, so the two behave almost identically once inside.

Is Testosterone enanthate bigger than Testosterone cypionate?

Testosterone cypionate is the heavier molecule, 412.6 g/mol against 400.6 g/mol for Testosterone enanthate. Testosterone enanthate is C26H40O3 and Testosterone cypionate is C27H40O3.