Quercetin vs Resveratrol: what is the difference?
Quercetin is a flavonoid with three rings and five hydroxyl groups, common in onions and tea, while resveratrol is a simpler stilbene from grape skin.
Sources and notes
- The sentence under the titlefrom sourceMoleculeFinder comparison notesThe pair's answer line.
- The two drawingscomputedMoleculeFinder rule (RDKit MCS)Each molecule's own drawing, as its page shows it. The common core, 8 of 22 atoms, is too small to align on.
Side by side
| Quercetin | Resveratrol | |
|---|---|---|
| Molecular weightCalculated PubChem | 302.23 g/molC15H10O7 | 228.24 g/molC14H12O3 |
| Hydrogen-bond donorsCalculated PubChem | 5 | 3 |
| Where each turns upEditorial MoleculeFinder food and product lists |
|
|
| FamilyEditorial MoleculeFinder curated | Flavonoids | Phenolic compounds |
| Everyday groupEditorial MoleculeFinder curated | Plant | Plant |
| Chemical groupsCalculated Found by rule (RDKit) | Aromatics, Phenols | Aromatics, Phenols |
| Hazard labelReported ECHA via PubChem | Danger | Danger |
| The supplier-filed hazard label's signal word, not a statement about ordinary use. | ||
| Oral LD50Measured HSDB via PubChem | 161 mg/kgpure quercetin, rat, oral | Not recorded |
| A single acute animal measure. It ranks nothing about human safety. | ||
Sources and notes
- Molecular weightcomputedPubChemComputed from the structure; the formula is under each weight.
- Hydrogen-bond donorscomputedPubChemThe hydrogens on nitrogen or oxygen that each molecule can lend to a hydrogen bond, counted from its structure.
- Where each turns upfrom sourceMoleculeFinder food and product listsEach amount is an editorial figure from our lists, not a measurement of any one product. Each mark is set by hand on the list, never inferred.
- Familyfrom sourceMoleculeFinder curated
- Everyday groupfrom sourceMoleculeFinder curated
- Chemical groupscomputedFound by rule (RDKit)Each group is found in the structure by a chemical pattern.
- Hazard labelfrom sourceECHA via PubChem
- Oral LD50from sourceHSDB via PubChem
- ECHAfrom sourceAttributionSource: European Chemicals Agency, echa.europa.eu.
- Identifiersfrom sourcePubChemPubChem CID 5280343 (Quercetin) and 445154 (Resveratrol).
In more detail
Both are plant polyphenols sold as antioxidant supplements and they belong to different classes. Quercetin is a flavonoid, a three-ring structure with five hydroxyl groups, concentrated in onion skin, capers, apples and tea. Resveratrol is a much simpler stilbene, two rings joined by a double bond, found in grape skin, red wine and Japanese knotweed, and it became famous through the French paradox. Both are poorly absorbed and rapidly conjugated by the liver, which is the central difficulty in translating their laboratory activity into anything measured in people. Quercetin is the heavier at 302.2 against 228.24.
Sources and notes
- The paragraphfrom sourceMoleculeFinder comparison notes
Questions
- What is the difference between Quercetin and Resveratrol?
- Quercetin is a flavonoid with three rings and five hydroxyl groups, common in onions and tea, while resveratrol is a simpler stilbene from grape skin.
- Is Quercetin bigger than Resveratrol?
- Quercetin is the heavier molecule, 302.23 g/mol against 228.24 g/mol for Resveratrol. Quercetin is C15H10O7 and Resveratrol is C14H12O3.
Sources and notes
- The answersfrom sourceMoleculeFinderThe first is the pair's answer line; the others are read off the table above.